Acta Biologica Hungarica

, Volume 53, Issue 1–2, pp 33–41 | Cite as

Somato-Dendritic Synapses in the Nucleus Reticularis Thalami of the Rat

  • B. CsillikEmail author
  • Á. Pálfi
  • K. Gulya
  • A. Mihály
  • Elizabeth Knyihár-Csillik


In the reticular nucleus of the rat thalamus, about 30% of the synapses are brought about by the perikarya of parvalbumin-immunopositive neurons, which establish somato-dendritic synapses with large dendrites of nerve cells of specific thalamic nuclei. Although the parvalbumin-immunopositive presynaptic structures bear resemblance to goblet-like or calyciform axonal endings, electron microscopic immunocytochemistry and in situ hybridization revealed that these structures are parts of the perikaryal cytoplasm studded with synaptic vesicles. In about 15% of the somato-dendritic synapses, axons are seen to be in synaptic contact with the parvalbumin-immunoreactive perikaryon. Double immunohistochemical staining revealed that the parvalbumin immunoreactive presynaptic perikarya and dendrites contained GABA. It is assumed that the peculiar somato-dendritic synaptic complexes subserve the goal of filtration of impulses arriving at the reticular nucleus from various thalamic nuclei, thus processing them for further sampling.


Thalamus reticular nucleus parvalbumin GABA somato-dendritic synapses 


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© Akadémiai Kiadó, Budapest 2002

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • B. Csillik
    • 1
    Email author
  • Á. Pálfi
    • 2
  • K. Gulya
    • 2
  • A. Mihály
    • 1
  • Elizabeth Knyihár-Csillik
    • 3
  1. 1.Department of AnatomyUniversity of SzegedSzegedHungary
  2. 2.Department of Zoology and CytologyUniversity of SzegedSzegedHungary
  3. 3.Department of Neurology, Albert Szent-Györgyi Medical and Pharmaceutical CenterUniversity of SzegedSzegedHungary

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