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Acta Biologica Hungarica

, Volume 52, Issue 2–3, pp 265–269 | Cite as

Cell Density-Correlated Induction of Pyruvate Decarboxylase Under Aerobic Conditions in the Yeast Pichia Stipitis

  • M. Mergler
  • U. KlinnerEmail author
Article

Abstract

During the aerobic batch cultivation of P. stipitis CBS 5776 with glucose, pyruvate decarboxylase was activated in a cell number-correlated manner. Activation started when a cell number between 7×107 and 1×108 cells ml−1 was reached and the enzyme activity increased during further cultivation. This induction might have been triggered either by an unknown quorum sensing system or by a shortage of cytoplasmic acetyl-CoA.

Keywords

Pyruvate decarboxylase Pichia stipitis aerobic activity 

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Copyright information

© Akadémiai Kiadó, Budapest 2001

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  1. 1.Institut für Biologie IV (Mikrobiologie), Lehr- und Forschungsgebiet Angewandte Mikrobiologie, Worringer WegRWTHAachenGermany

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