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Acta Biologica Hungarica

, Volume 69, Issue 1, pp 110–113 | Cite as

Smallest Lectin-Like Peptide Identified from the Skin Secretion of an Endemic Frog, Hydrophylax Bahuvistara

  • Thundiparampil Vasanth Vineethkumar
  • Gopal Shyla
  • Sanil GeorgeEmail author
Short Communication
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Abstract

Lectins are sugar-binding proteins and considered as attractive candidates for drug delivery and targeting. Here, we report the identifcation of the smallest lectin-like peptide (odorranalectin HYba) from the skin secretion of Hydrophylax bahuvistara which is being the shortest lectin-like peptide identifed so far from the frog skin secretion, with 15 amino acid residues. The peptide is the frst report from an Indian frog and lacks antimicrobial activity but strongly agglutinate intact human erythrocytes. The sequences at the L-fucose recognizing region is conserved as in other lectins reported from frog skin secretion and could be exploited for specifcity and drug targeting properties.

Keywords

Agglutination amphibian antimicrobial Hydrophylax lectin 

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Copyright information

© Akadémiai Kiadó Zrt. 2018

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • Thundiparampil Vasanth Vineethkumar
    • 1
  • Gopal Shyla
    • 1
  • Sanil George
    • 1
    Email author
  1. 1.Chemical and Environmental Biology groupRajiv Gandhi Centre for BiotechnologyThiruvananthapuramIndia

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