Phytochemical Investigation of Rumex Thyrsiflorus Fingerh.

Abstract

In the course of our pharmacological screening of Polygonaceae species occurring in the Carpathian Basin the extracts prepared from the roots of Rumex thyrsiflorus showed promising antiproliferative, xanthine oxidase inhibitory and antibacterial activities. The present work deals with the isolation of compounds from the root of the plant. After multistep separation process, four compounds were obtained from the n-hexane, chloroform and ethyl acetate soluble fractions of the methanol extract of the root. The structures of the isolated compounds were determined as 1-palmitoylglycerol, β-sitosterol, (–)-epicatechin, and procyanidin B5.

References

  1. 1.

    Allen, D. E., Hatfield, G. (2004). Medicinal plants in folk tradition–An ethnobotany of Britain and Ireland. Timber Press, Portland, Cambridge.

    Google Scholar 

  2. 2.

    Cui, C. B., Tezuka, Y., Kikuchi, T., Nakano, H., Tamaoki, T., Park, J. H. (1992) Constituents of a fern. Davallia mariesii Moore. II. Identification and 1H- and 13C-Nuclear Magnetic Resonance spectra of procyanidin B-5, epicatechin-(4β→8)-epicatechin-(4β→6)-epicatechin, and epicatechin-(4β→6)- epicatechin- epicatechin-(4β→8)-(4β→6)-epicatechin. Chem. Pharm. Bull. 40, 889–898.

    CAS  Article  Google Scholar 

  3. 3.

    Csupor-Löffler, B., Hajdú, Z., Zupkó, I., Molnár, J., Forgo, P., Vasas, A., Kele, Z., Hohmann, J. (2011) Antiproliferative constituents of the roots o. Conyza canadensis. Planta Med. 77, 1183–1188.

    Article  Google Scholar 

  4. 4.

    Dénes, A., Papp, N., Babai, D., Czúcz, B., Molnár, Z. (2013) Edible wild plants and their use based on ethnographic and ethnobotanical researches among Hungarian in the Carpathian Basin. Dunántúli Dolgozatok (A) Természettudományi Soroza. 13, 35–76.

    Google Scholar 

  5. 5.

    Getie, M., Gebre-Mariam, T., Rietz, R., Höhne, C., Huschka, C., Schmidtke, M., Abate, A., Neubert, R. H. H. (2003) Evaluation of the antimicrobial and anti-inflammatory activities of the medicinal plant. Dodonaea viscosa. Rumex nervosus an. Rumex abyssinicus. Fitoterapia 74, 139–143.

    CAS  Article  Google Scholar 

  6. 6.

    Hirao, S., Tara, K., Kuwano, K., Tanaka, J., Ishibashi, F. (2012) Algicidal activity of glycerolipids from brown alg. Ishige sinicola toward red tide microalgae. Biosci. Biotechnol. Biochem. 76, 372–374.

    CAS  Article  Google Scholar 

  7. 7.

    Lajter, I., Zupkó, I., Molnár, J., Jakab, G., Balogh, L., Vasas, A., Hohmann, J. (2013) Antiproliferative activity of Polygonaceae species from the Carpathian Basin against human cancer cell lines. Phytother. Res. 27, 77–85.

    Article  Google Scholar 

  8. 8.

    Litvinenko, Y. A., Muzychkina, R. A. (2003) Phytochemical investigation of biologically active substances in certain Kazakhsta. Rumex species. 1. Chem. Nat. Comp. 39, 446–449.

    CAS  Article  Google Scholar 

  9. 9.

    Martins, A., Vasas, A., Schelz, Z., Viveiros, M., Molnár, J., Hohmann, J., Amaral, L. (2010) Constituents o. Carpobrotus edulis inhibit P-glycoprotein o. MDR1-transfected mouse lymphoma cells. Anticancer Res. 30, 829–836.

    CAS  PubMed  Google Scholar 

  10. 10.

    Martins, A., Vasas, A., Viveiros, M., Molnár, J., Hohmann, J., Amaral, L. (2011) Antibacterial properties of compounds isolated fro. Carpobrotus edulis. Int. J. Antimicrob. Ag. 37, 438–444.

    CAS  Article  Google Scholar 

  11. 11.

    Ododo, M. M., Choudhury, M. K., Dekebo, A. H. (2016) Structure elucidation of β-sitosterol with antibacterial activity from the root bark o. Malva parviflora. SpringerPlus 5, 1–11.

    CAS  Article  Google Scholar 

  12. 12.

    Orbán-Gyapai, O., Lajter, I., Hohmann, J., Jakab, G., Vasas, A. (2015) Xanthine oxidase inhibitory activity of extracts prepared from Polygonaceae species. Phytother. Res. 29, 459–465.

    Article  Google Scholar 

  13. 13.

    Orbán-Gyapai, O., Liktor-Busa, E., Kúsz, N., Stefkó, D., Urbán, E., Hohmann, J., Vasas, A. (2017) Antibacterial screening o. Rumex species native to the Carpathian Basin and bioactivity-guided isolation of compounds fro. Rumex aquaticus. Fitoterapia 118, 103–106.

    Article  Google Scholar 

  14. 14.

    Özyürek, M., Bektaşoğlu, B., Güçlü, K., Apak, R. (2009) Measurement of xanthine oxidase inhibition activity of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method. Anal. Chim. Acta 636, 42–50.

    Article  Google Scholar 

  15. 15.

    Pardo-de-Santayana, M., Tardío, J., Morales, R. (2005) The gathering and consumption of wild edible plants in the Campoo (Cantabria, Spain). Int. J. Food Sci. Nutr. 56, 529–542.

    Article  Google Scholar 

  16. 16.

    Shahat, A. A. (2006) Procyanidins fro. Adansonia digitata. Pharm. Biol. 44, 445–450.

    CAS  Article  Google Scholar 

  17. 17.

    Vasas, A., Orbán-Gyapai, O., Hohmann, J. (2015) The genu. Rumex: Review of traditional uses, phytochemistry and pharmacology. J. Ethnopharmacol. 175, 198–228.

    CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Andrea Vasas.

Rights and permissions

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Orbán-Gyapai, O., Forgo, P., Hohmann, J. et al. Phytochemical Investigation of Rumex Thyrsiflorus Fingerh.. BIOLOGIA FUTURA 68, 232–236 (2017). https://doi.org/10.1556/018.68.2017.2.10

Download citation

Keywords

  • Rumex thyrsiflorus
  • Polygonaceae
  • phenolic compounds
  • procyanidin