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Acta Biologica Hungarica

, Volume 67, Issue 1, pp 112–120 | Cite as

Characterisation of Mitochondrial Haplotypes Occurred in a Candida Albicans Population

  • Ilona PfeifferEmail author
  • Zoltán Farkas
  • Judit Kucsera
  • Muthusamy Chandrasekaran
  • Shine Kadaikunnan
  • Naiyf S. Alharbi
  • Csaba Vágvölgyi
Article

Abstract

The genetic background of mitochondrial DNA polymorphism in Candida albicans was studied by physical and functional mapping of four haplotypes identified recently in a hospital-population. The restriction patterns revealed considerable differences; however, the size of the mitochondrial DNA did not vary significantly. Sequence data demonstrated that size differences arose by short deletions, while restriction fragment length polymorphisms are caused by nucleotide substitutions in single sites. Gene rearrangement could not be detected; nevertheless, the coincidence of nucleotide substitution pattern in the inverted repeat region suggested the occurrence of homologue recombination.

Keywords

Candida albicans mitochondrial DNA sequences PCR 

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Copyright information

© Akadémiai Kiadó, Budapest 2016

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • Ilona Pfeiffer
    • 1
    Email author
  • Zoltán Farkas
    • 1
  • Judit Kucsera
    • 1
  • Muthusamy Chandrasekaran
    • 2
  • Shine Kadaikunnan
    • 2
  • Naiyf S. Alharbi
    • 2
  • Csaba Vágvölgyi
    • 1
    • 2
  1. 1.Department of Microbiology, Faculty of Science and InformaticsUniversity of SzegedSzegedHungary
  2. 2.Botany and Microbiology DepartmentKing Saud UniversityRiyadhKingdom of Saudi Arabia

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