Acta Biologica Hungarica

, Volume 67, Issue 1, pp 75–84 | Cite as

Synthesis and Antimicrobial Evaluation of Some Novel Sulfonylamido-Benzoxazoles

  • Ozlem Temiz-ArpaciEmail author
  • Fatma Doğanc
  • Duygu Sac
  • Elmas Sari
  • Fatma Kaynak-Onurdag
  • Suzan Okten


A series of 2-(p-substituted phenyl)-5-[(4-substituted phenyl) sulfonylamido]-benzoxazoles were synthesized and tested for their antimicrobial activities. The structures of the new derivatives were elucidated by spectral techniques. The minimum inhibitory concentrations (MIC) of the new benzoxazoles were determined against standard bacterial and fungal strains and drug-resistant isolates and compared to those of several reference drugs.


Benzoxazole sulfonylamides antibacterial activity antifungal activity synthesis 


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© Akadémiai Kiadó, Budapest 2016

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • Ozlem Temiz-Arpaci
    • 1
    Email author
  • Fatma Doğanc
    • 1
  • Duygu Sac
    • 1
  • Elmas Sari
    • 1
  • Fatma Kaynak-Onurdag
    • 2
  • Suzan Okten
    • 2
  1. 1.Faculty of Pharmacy, Department of Pharmaceutical ChemistryAnkara UniversityTandogan, AnkaraTurkey
  2. 2.Faculty of Pharmacy, Department of Pharmaceutical MicrobiologyTrakya UniversityEdirneTurkey

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