International Journal of Hematology

, Volume 79, Issue 3, pp 250–252 | Cite as

Granulocytic sarcoma presenting with malignant anasarca in a patient with secondary acute myeloid leukemia

  • Mohammad Y. Khan
  • Khader K. Hussein
  • Max G. Walter
  • Muhammad K. Hasan
  • William Kern
  • Mohamed A. Kharfan-Dabajaa
Case Report


Granulocytic sarcomas (GS) are rare extramedullary tumor masses composed of immature cells derived from the hematopoietic myeloid series. GS occur in 3% to 7% of cases of acute myeloid leukemia (AML) and can present before, during, or even after the diagnosis of AML. GS can involve different organs, individually or simultaneously, including the skin, lymph nodes, bone, breast, central nervous system, and lung among others. GS involving peritoneal and pleural fluids is a rare presentation. We present an unusual case of a patient with myelodysplastic syndrome whose disease progressed into a secondary AML and developed GS in the ascitic and pleural effusions as the predominant manifestation of disease progression.

Key words

Acute myeloid leukemia Ascites Chloromas Granulocytic sarcomas Myelodysplastic syndromes 


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Copyright information

© The Japanese Society of Hematology 2004

Authors and Affiliations

  • Mohammad Y. Khan
    • 1
  • Khader K. Hussein
    • 2
  • Max G. Walter
    • 3
  • Muhammad K. Hasan
    • 4
  • William Kern
    • 5
  • Mohamed A. Kharfan-Dabajaa
    • 4
  1. 1.Section of Hematology-OncologyUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA
  2. 2.Cancer Care AssociatesOklahoma CityUSA
  3. 3.Departments of RadiologyUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA
  4. 4.Departments of Internal MedicineUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA
  5. 5.Departments of PathologyUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA

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