Dilated Cardiomyopathy during the Course of Hemolytic Uremic Syndrome


A 47-year-old woman presented with severe hemolytic uremic syndrome (HUS) followed by heart failure. An echocardiogram showed an ejection fraction of 20%, and a cardiac catheterization followed by a myocardial histologic evaluation demonstrated dilated cardiomyopathy. Plasma exchange and hemodialysis were performed regularly. The later outcomes of renal function and cardiomyopathy were favorable. A review of the literature confirmed the rare and severe nature of cardiac lesions occurring in the course of HUS. This case indicates the importance of cardiac monitoring in HUS and the need for prolonged support.

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Correspondence to Alexandra Alexopoulou or Spyros P. Dourakis or Christos Zovoilis or Emmanouel Agapitos or Aris Androulakis or Anna Filiotou or Athanasios J. Archimandritis.

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Alexopoulou, A., Dourakis, S.P., Zovoilis, C. et al. Dilated Cardiomyopathy during the Course of Hemolytic Uremic Syndrome. Int J Hematol 86, 333–336 (2007). https://doi.org/10.1532/IJH97.E0713

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Key words

  • Hemolytic uremic syndrome
  • Heart failure
  • Cardiomyopathy