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Primary Cutaneous Plasmacytoma after Rejection of a Transplanted Kidney: Case Report and Review of the Literature

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Abstract

Immunosuppressed organ allograft recipients are at risk of developing lymphomas and lymphoproliferative disorders as a consequence of immunosuppressive therapy and long-term antigenic stimulation from both the graft and possible viral infections. No more than 4% of the malignant tumors detected in organ recipients are plasmacytomas. Primary cutaneous plasmacytoma is a rare type of cutaneous B-cell lymphoma arising primarily in the skin. It is derived from clonally expanded plasma cells with various degrees of maturation and atypia. We report the occurrence of a solitary cutaneous plasmacytoma in a 56-year-old male patient undergoing hemodialysis after rejection of a grafted kidney. The diagnosis was made a few months after the kidney had been surgically removed. A thorough examination showed no evidence of systemic disease. Skin lesions were successfully treated with local radiotherapy. After 2 years of follow-up there were no local or systemic recurrences.

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Authors and Affiliations

  1. Departments of Dermatology, University of Verona, Ospedale Civile Maggiore Piazzale Stefani 1, 37126, Verona (VR), Italy

    Gianpaolo Tessari & Annalisa Barba

  2. Departments of Nephrology, University of Verona, Ospedale Civile Maggiore Piazzale Stefani 1, 37126, Verona (VR), Italy

    Fabio Fabbian, Vittorio Ortalda & Lucia Cavallini

  3. Departments of Pathology, University of Verona, Ospedale Civile Maggiore Piazzale Stefani 1, 37126, Verona (VR), Italy

    Chiara Colato

  4. Bone Marrow Transplant Unit, Azienda Ospedaliera di Verona, Verona, Italy

    Fabio Benedetti

  5. Transfusion Service, Azienda Ospedaliera di Verona, Verona, Italy

    Massimo Franchini

Authors
  1. Gianpaolo Tessari
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  2. Fabio Fabbian
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  3. Chiara Colato
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  4. Fabio Benedetti
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  5. Massimo Franchini
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  6. Vittorio Ortalda
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  7. Lucia Cavallini
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  8. Annalisa Barba
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Correspondence to Gianpaolo Tessari.

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Tessari, G., Fabbian, F., Colato, C. et al. Primary Cutaneous Plasmacytoma after Rejection of a Transplanted Kidney: Case Report and Review of the Literature. Int J Hematol 80, 361–364 (2004). https://doi.org/10.1532/IJH97.E0406

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  • DOI: https://doi.org/10.1532/IJH97.E0406

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