Abstract
Primary renal lymphoma (PRL) is a rare form of extranodal non-Hodgkin’s lymphoma often diagnosed and treated by oncologists and urologists. Pathophysiological and clinical data on PRL are sparse, but the limited reported experience suggests the disease usually has an ominous outcome. As in other renal tumors, comprehensive radiological investigations have a central role in the recognition and final diagnosis of PRL. We describe the presenting features and clinical course of an elderly woman who was found to have PRL after evaluation for persistent low-grade fever. Diagnostic and therapeutic caveats are discussed on the basis of a critical literature review of case reports and descriptions of small series of patients.
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References
Freeman C, Berg JW, Cutler SJ. Occurrence and prognosis of extranodal lymphomas.Cancer. 1972;29:252–260.
Pervez H, Shaikh M, Potti A, Mehdi SA. Uncommon presentations of non-Hodgkin’s lymphoma: case 3—primary renal lymphoma.J Clin Oncol. 2003;21:567–569.
Stallone G, Infante B, Manno C, Campobasso N, Pannarale G, Schena FP. Primary renal lymphoma does exist.J Nephrol. 2000;13:367–372.
Okuno SH, Hoyler JD, Ristow K, Witzig TE. Primary renal non-Hodgkin’s lymphoma: an unusual extra nodal site.Cancer. 1995;75:2258–2261.
Saito S. Primary renal lymphoma: case report and review of the literature.Urol Int. 1996;56:192–195.
Knockaert DC, Vanneste LJ, Bobbaers HJ. Fever of unknown origin in elderly patients.J Am Geriatr Soc. 1993;41:1187–1192.
Norman DC, Yoshikawa TT. Fever in the elderly.Infect Dis Clin North Am. 1996;10:93–101.
Kandel LB, McCullough DL, Harrison LH, Woodruff RD, Ahl ET, Munitz HA. Primary renal lymphoma. Does it exist?Cancer. 1987; 60:386–391.
Gellrich J, Hakenberg OW, Naumann R, Manseck A, Lossnitzer A, Wirth MP. Primary renal non-Hodgkin’s lymphoma: a difficult differential diagnosis.Onkologie. 2002;25:273–277.
Tuzel E, Mungan MU, Yorukoglu K, Basakci A, Kirkali Z. Primary renal lymphoma of mucosa-associated lymphoid tissue.Urology. 2003;61:463–464.
Urban BA, Fishman EK. Renal lymphoma: CT patterns with emphasis on helical CT.Radiographics. 2000;20:197–212.
Truong LD, Caraway N, Ngo T, Laucirica R, Katz R, Ramzy I. Renal lymphoma: the diagnostic and therapeutic roles of fine-needle aspiration.Am J Clin Pathol. 2001;115:18–31.
Johnson PT, Nazarian LN, Feld RI, et al. Sonographically guided renal mass biopsy: indications and efficacy. JUltrasound Med. 2001; 20:749–753.
Farrell JJ, Brugge WR. EUS-guided fine-needle aspiration of a renal mass: an alternative method for diagnosis of malignancy.Gastrointest Endosc. 2002;56:450–452.
Sheeran SR, Sussman SK. Renal lymphoma: spectrum of CT findings and potential mimics.AJR Am J Roentgenol. 1995;164:363–370.
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Zomas, A., Leivada, A., Gortzolidis, G. et al. Primary Renal Lymphoma Presenting with Chronic Low-Grade Fever. Int J Hematol 79, 361–363 (2004). https://doi.org/10.1532/IJH97.E0320
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DOI: https://doi.org/10.1532/IJH97.E0320