Advertisement

International Journal of Hematology

, Volume 79, Issue 4, pp 361–363 | Cite as

Primary Renal Lymphoma Presenting with Chronic Low-Grade Fever

  • A. Zomas
  • A. Leivada
  • G. Gortzolidis
  • E. Michalis
  • A. Skandalis
  • N. I. Anagnostopoulos
Case Report

Abstract

Primary renal lymphoma (PRL) is a rare form of extranodal non-Hodgkin’s lymphoma often diagnosed and treated by oncologists and urologists. Pathophysiological and clinical data on PRL are sparse, but the limited reported experience suggests the disease usually has an ominous outcome. As in other renal tumors, comprehensive radiological investigations have a central role in the recognition and final diagnosis of PRL. We describe the presenting features and clinical course of an elderly woman who was found to have PRL after evaluation for persistent low-grade fever. Diagnostic and therapeutic caveats are discussed on the basis of a critical literature review of case reports and descriptions of small series of patients.

Key words

Renal tumors Chronic fever Non-Hodgkin’s lymphoma Extranodal lymphoma Nephrectomy 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Freeman C, Berg JW, Cutler SJ. Occurrence and prognosis of extranodal lymphomas.Cancer. 1972;29:252–260.CrossRefGoogle Scholar
  2. 2.
    Pervez H, Shaikh M, Potti A, Mehdi SA. Uncommon presentations of non-Hodgkin’s lymphoma: case 3—primary renal lymphoma.J Clin Oncol. 2003;21:567–569.CrossRefGoogle Scholar
  3. 3.
    Stallone G, Infante B, Manno C, Campobasso N, Pannarale G, Schena FP. Primary renal lymphoma does exist.J Nephrol. 2000;13:367–372.Google Scholar
  4. 4.
    Okuno SH, Hoyler JD, Ristow K, Witzig TE. Primary renal non-Hodgkin’s lymphoma: an unusual extra nodal site.Cancer. 1995;75:2258–2261.CrossRefGoogle Scholar
  5. 5.
    Saito S. Primary renal lymphoma: case report and review of the literature.Urol Int. 1996;56:192–195.CrossRefGoogle Scholar
  6. 6.
    Knockaert DC, Vanneste LJ, Bobbaers HJ. Fever of unknown origin in elderly patients.J Am Geriatr Soc. 1993;41:1187–1192.CrossRefGoogle Scholar
  7. 7.
    Norman DC, Yoshikawa TT. Fever in the elderly.Infect Dis Clin North Am. 1996;10:93–101.CrossRefGoogle Scholar
  8. 8.
    Kandel LB, McCullough DL, Harrison LH, Woodruff RD, Ahl ET, Munitz HA. Primary renal lymphoma. Does it exist?Cancer. 1987; 60:386–391.CrossRefGoogle Scholar
  9. 9.
    Gellrich J, Hakenberg OW, Naumann R, Manseck A, Lossnitzer A, Wirth MP. Primary renal non-Hodgkin’s lymphoma: a difficult differential diagnosis.Onkologie. 2002;25:273–277.Google Scholar
  10. 10.
    Tuzel E, Mungan MU, Yorukoglu K, Basakci A, Kirkali Z. Primary renal lymphoma of mucosa-associated lymphoid tissue.Urology. 2003;61:463–464.CrossRefPubMedGoogle Scholar
  11. 11.
    Urban BA, Fishman EK. Renal lymphoma: CT patterns with emphasis on helical CT.Radiographics. 2000;20:197–212.CrossRefGoogle Scholar
  12. 12.
    Truong LD, Caraway N, Ngo T, Laucirica R, Katz R, Ramzy I. Renal lymphoma: the diagnostic and therapeutic roles of fine-needle aspiration.Am J Clin Pathol. 2001;115:18–31.CrossRefPubMedPubMedCentralGoogle Scholar
  13. 13.
    Johnson PT, Nazarian LN, Feld RI, et al. Sonographically guided renal mass biopsy: indications and efficacy. JUltrasound Med. 2001; 20:749–753.CrossRefPubMedPubMedCentralGoogle Scholar
  14. 14.
    Farrell JJ, Brugge WR. EUS-guided fine-needle aspiration of a renal mass: an alternative method for diagnosis of malignancy.Gastrointest Endosc. 2002;56:450–452.CrossRefPubMedPubMedCentralGoogle Scholar
  15. 15.
    Sheeran SR, Sussman SK. Renal lymphoma: spectrum of CT findings and potential mimics.AJR Am J Roentgenol. 1995;164:363–370.CrossRefGoogle Scholar

Copyright information

© The Japanese Society of Hematology 2004

Authors and Affiliations

  • A. Zomas
    • 1
  • A. Leivada
    • 1
  • G. Gortzolidis
    • 1
  • E. Michalis
    • 1
  • A. Skandalis
    • 1
  • N. I. Anagnostopoulos
    • 1
  1. 1.Department of Clinical HaematologyG. Gennimatas Regional General Hospital of AthensAthensGreece

Personalised recommendations