Abstract
Five patients with mucosa-associated lymphoid tissue (MALT) lymphoma (Helicobacter pylori negative) were initially treated with daily chlorambucil (Chl, 0.06–0.08 mg/kg per day) and achieved complete remission (n = 4) or partial remission (n = 1).They were then given long-term weekly Chl as maintenance therapy with good results. One patient came off treatment and has remained in continued remission for 44 months. This simple, low-cost, and convenient approach deserves further evaluation in patients with MALT lymphoma and other indolent and incurable lymphoproliferative disorders. doi: 10.1532/IJH97.A20308
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Manoharan, A. Sustained Remissions with Long-term Weekly Chlorambucil Maintenance Therapy in Patients with Mucosa-Associated Lymphoid Tissue Lymphoma. Int J Hematol 79, 472–473 (2004). https://doi.org/10.1532/IJH97.A20308
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DOI: https://doi.org/10.1532/IJH97.A20308