International Journal of Hematology

, Volume 79, Issue 3, pp 298–302 | Cite as

Spontaneous pneumothorax developed in patients with bronchiolitis obliterans after unrelated hematopoietic stem cell transplantation: case report and review of the literature

  • Ho -Jin Shin
  • Chi Young Park
  • Yun Hee Park
  • Yoo Jin Kim
  • Chang -Ki Min
  • Seok Lee
  • Dong -Wook Kim
  • Jong Wook Lee
  • Woo Sung Min
  • Chun Choo Kim
Case Report

Abstract

Spontaneous pneumothorax following unrelated hematopoietic stem cell transplantation developed in our 2 patients with bronchiolitis obliterans. Bronchiolitis obliterans is a form of obstructive airway disease and is considered a manifestation of chronic graft-versus-host disease (GVHD). Both of the patients were the recipients of marrow from HLA-matched unrelated donors after a preparative regimen with total body irradiation. Chronic GVHD after transplantation is a common feature in these cases. In contrast to other patients with pneumothorax described in the literature, our patients did not develop bullae.We describe a pneumothorax secondary to bronchiolitis obliterans that complicated the posttransplantation course.

Key words

Pneumothorax Bronchiolitis obliterans Hematopoietic stem cell transplantation 

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Copyright information

© The Japanese Society of Hematology 2004

Authors and Affiliations

  • Ho -Jin Shin
    • 1
  • Chi Young Park
    • 2
  • Yun Hee Park
    • 3
  • Yoo Jin Kim
    • 3
  • Chang -Ki Min
    • 3
  • Seok Lee
    • 3
  • Dong -Wook Kim
    • 3
  • Jong Wook Lee
    • 3
  • Woo Sung Min
    • 3
  • Chun Choo Kim
    • 3
  1. 1.Department of Internal Medicine, College of MedicinePusan National UniversityBusan
  2. 2.Department of Internal MedicineChosun University College of MedicineGwangju
  3. 3.Division of Hematology, Catholic Hematopoietic Stem Cell Transplantation Center, College of MedicineThe Catholic University of KoreaSeoulKorea

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