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Development of Mast Cells: Analysis with Mutant Mice

International Journal of Hematology volume 86, pages 22–26 (2007)Cite this article

Abstract

Mast cells are the progeny of hematopoietic stem cells. Mutant mice lacking mast cells or possessing abnormal mast cells, such asW/W v,Sl/Sl d, andmi/mi, are useful for investigating the developmental process. Recently, mast cell progenitors were identified with sorting techniques. Recent progress in research into mast cell development is reviewed.

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Affiliations

  1. Department of Pathology, Osaka University School of Medicine, 2-2 Yamada-oka, Suita, 565-0871, Osaka, Japan

    Eiichi Morii

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  1. Eiichi Morii
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Cite this article

Morii, E. Development of Mast Cells: Analysis with Mutant Mice. Int J Hematol 86, 22–26 (2007). https://doi.org/10.1532/IJH97.07053

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  • DOI: https://doi.org/10.1532/IJH97.07053

Key words

  • Mast cells
  • KIT
  • Stem cell factor
  • MITF
  • Surface markers