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Successful Treatment with Imatinib Combined with Less Intensive Chemotherapy (Vincristine and Dexamethasone) as Induction Therapy in a Very Elderly Patient with Philadelphia Chromosome—Positive Acute Lymphoblastic Leukemia

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References

  1. Dombret H, Gabert J, Boiron JM, et al. Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia: results of the prospective multicenter LALA-94 trial.Blood. 2002;100:2357–2366.

    Article  CAS  Google Scholar 

  2. Avivi I, Goldstone AH. Bone marrow transplant in Ph+ ALL patients.Bone Marrow Transplant. 2003;31:623–632.

    Article  CAS  Google Scholar 

  3. Iida H, Sao H, Kitaori K, et al. Twenty years’ experience in allo-geneic hematopoietic stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia in the Nagoya Blood and Marrow Transplantation Group.Int J Hematol. 2004;79:79–84.

    Article  Google Scholar 

  4. Thomas DA, Faderl S, Cortes J, et al. Treatment of Philadelphia chromosome-positive acute lymphocytic leukemia with hyper-CVAD and imatinib mesylate.Blood. 2004;103:4396–4407.

    Article  CAS  Google Scholar 

  5. Towatari M, Yanada M, Usui N, et al. Combination of intensive chemotherapy and imatinib can rapidly induce high-quality complete remission for a majority of patients with newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia.Blood. 2004;104:3507–3512.

    Article  CAS  Google Scholar 

  6. Yanada M, Takeuchi J, Sugiura I, et al. High complete remission rate and promising outcome by combination of imatinib and chemotherapy for newly diagnosed BCR-ABL-positive acute lymphoblastic leukemia: a phase II study by the Japan Adult Leukemia Study Group.J Clin Oncol. 2006;24:460–466.

    Article  CAS  Google Scholar 

  7. Wassmann B, Pfeifer H, Goekbuget N, et al. Alternating versus concurrent schedules of imatinib and chemotherapy as front-line therapy for Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL).Blood. 2006;108:1469–1477.

    Article  CAS  Google Scholar 

  8. Rea D, Legros L, Raffoux E, et al. High-dose imatinib mesylate combined with vincristine and dexamethasone (DIV regimen) as induction therapy in patients with resistant Philadelphia-positive acute lymphoblastic leukemia and lymphoid blast crisis of chronic myeloid leukemia.Leukemia. 2006;20:400–403.

    Article  CAS  Google Scholar 

  9. Ottman OG, Wassmann B, Goekbuget N, et al. A randomized phase II study comparing imatinib with chemotherapy as induction therapy in elderly patients with newly diagnosed Philadelphia-positive acute lymphoid leukemias (Ph+ ALL) [abstract].Hematol J. 2004;5:S112..

    Article  CAS  Google Scholar 

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Correspondence to Kazuhiro Nishii.

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Nishii, K., Sakakura, M., Tsukada, T. et al. Successful Treatment with Imatinib Combined with Less Intensive Chemotherapy (Vincristine and Dexamethasone) as Induction Therapy in a Very Elderly Patient with Philadelphia Chromosome—Positive Acute Lymphoblastic Leukemia. Int J Hematol 85, 273–274 (2007). https://doi.org/10.1532/IJH97.06216

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  • DOI: https://doi.org/10.1532/IJH97.06216

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