International Journal of Hematology

, Volume 79, Issue 3, pp 229–234 | Cite as

Second malignant neoplasms following hematopoietic stem cell transplantation

  • Debra L. FriedmanEmail author
  • Wendy Leisenring
  • Jeffrey L. Schwartz
  • H. Joachim Deeg
Progress in hematology


Hematopoietic stem cell transplantation is being successfully used to treat a variety of malignant and nonmalignant disorders. This therapy has resulted in an increasing number of survivors who are at risk for adverse long-term outcomes, including the development of second and subsequent malignant neoplasms.We review the incidence and spectrum of posttransplantation malignancies and discuss risk factors and future directions for research.

Key words

Posttransplantation malignancies Secondary cancers 


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Copyright information

© The Japanese Society of Hematology 2004

Authors and Affiliations

  • Debra L. Friedman
    • 1
    Email author
  • Wendy Leisenring
    • 1
  • Jeffrey L. Schwartz
    • 1
  • H. Joachim Deeg
    • 1
  1. 1.Fred Hutchinson Cancer Research CenterUniversity of WashingtonSeattleUSA

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