Abstract
We report a case of a 64-year-old woman treated with meglumine antimoniate (Glucantime®). On day 20, she developed fever, a pruriginous skin rash and myalgia. The blood tests showed eosinophilia and hepatic cytolysis. The clinico-biological picture improved gradually and the symptoms disappeared 4 weeks after the drug withdrawal. Six weeks later, intradermal tests to Glucantime® were performed and were positive at 48 hour-reading. This clinical picture suggests DRESS induced by meglumine antimoniate. To the best of our knowledge, only one case of meglumine antimoniate-induced DRESS has been reported in the literature and we are the first to report a case confirmed by skin tests.
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Chaabane, A., Romdhane, H.B., Brahim, H.B. et al. Meglumine antimoniate-induced DRESS: original case with a positive skin test. Acta Parasit. 63, 845–847 (2018). https://doi.org/10.1515/ap-2018-0104
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DOI: https://doi.org/10.1515/ap-2018-0104