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Association between immunoreactivity to Anisakis spp. antigens and high-risk pregnancy

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Abstract

Numerous factors contribute to perinatal risk, many of which remain undefined. This study sought to determine the frequency of fish intake in postpartum women, and to establish a relationship between the rates of immunoreactivity for antigens from Anisakis spp. and high-risk pregnancy. In this prospective noninterventional study, a structured questionnaire was administered and serum was collected from postpartum women at two perinatal centers (a high-risk birth unit [HRBU] and a low-risk birth unit [LRBU]) in the Niterói municipality of Brazil. Anisakis species-specific IgG and IgE were measured by ELISA. The chi-squared test was performed, and odds ratios (ORs) with their 95% confidence intervals were estimated. The t-test or Mann-Whitney test was applied to continuous, normally distributed variables. In total, 309 women (170 from HRBU, 139 from LRBU) between 24.8 and 26.7 years old with a median of 6 to 8 prenatal visits were enrolled. Women in the two units exhibited differences in some variables, including prenatal care (p = 0.01), maternal and fetal risk (p = 0.00; OR = 6.17), and gestational age (p = 0.00), but no differences in fish consumption (p = 0.29), frequency of fish intake (p = 0.40), allergic symptoms (p = 0.51), or frequency of anti-Anisakis reactivity (p = 0.22). Logistic regression analysis revealed that only age was independently associated with postpartum anti-Anisakis reactivity. This study confirmed a low prevalence of fish intake and suggested that Anisakis spp. had no impact on high-risk pregnancies among this postpartum study population.

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Authors and Affiliations

  1. Departamento Materno-Infantil, Faculdade de Medicina; Hospital Universitário Antônio Pedro, Universidade Federal Fluminense; Av. Marques do Paraná, 303; CEP: 24030-210, Centro, Niterói, Rio de Janeiro, Brasil

    Israel Figueiredo Jr

  2. Departamento de Imunobiologia, Instituto de Biologia, Universidade Federal Fluminense, Brasil

    Mauricio Vericimo, Taylane Ferreira & Gerlinde Teixeira

  3. Departamento Tecnologia de Produtos de Origem Animal, Faculdade de Veterinária, Universidade Federal Fluminense, Brasil

    Luciana Terra & Sergio Carmona São Clemente

Authors
  1. Israel Figueiredo Jr
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  2. Mauricio Vericimo
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  3. Luciana Terra
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  4. Taylane Ferreira
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  5. Sergio Carmona São Clemente
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  6. Gerlinde Teixeira
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Correspondence to Israel Figueiredo Jr.

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Figueiredo, I., Vericimo, M., Terra, L. et al. Association between immunoreactivity to Anisakis spp. antigens and high-risk pregnancy. Acta Parasit. 60, 609–613 (2015). https://doi.org/10.1515/ap-2015-0085

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  • DOI: https://doi.org/10.1515/ap-2015-0085

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