Skip to main content
Log in

Nonheart-beating donation in the neurologically devastated patient

  • Review
  • Published:
Neurocritical Care Aims and scope Submit manuscript

Abstract

A national shortage of organs for transplantation has led to a renewed interest in an old concept of using nonheart-beating organ donors as a source of organs for transplantation. Nonheart-beating donors are patients who have organ procurement obtained after death has been declared by cardiopulmonary criteria as opposed to the traditional heart-beating donor who has been declared dead by neurological criteria. The practice seems promising to increase the available organ supply. This article reviews the history, classification, protocols, and ethical issues involved with nonheart-beating organ donation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Recommendations for nonheartbeating organ donation. A position paper by the Ethics Committee, American College of Critical Care Medicine, Society of Critical Care Medicine. Crit Care Med 2001;29:1826–1831.

    Article  Google Scholar 

  2. Van Norman GA. Another matter of life and death: what every anesthesiologist should know about the ethical, legal, and policy implications of the non-heart-beating cadaver organ donor. Anesthesiology 2003;98:763–773.

    Article  PubMed  Google Scholar 

  3. A definition of irreversible coma. Report of the Ad Hoc Committee of the Harvard Medical School to Examine the Definition of Brain Death. J Am Med Assoc 1968;205:337–340.

    Article  Google Scholar 

  4. DeVita MA, Snyder JV, Grenvik A. History of organ donation by patients with cardiac death. Kennedy Inst Ethics J 1993;3:113–129.

    PubMed  CAS  Google Scholar 

  5. Not Quite Dead. In: 60 Minutes. USA: CBS Television, 1997.

  6. Institute of Medicine: Non-Heart-Beating Organ Transplantation: Medical and Ethical Issues of Procurement. Washington, DC.: National Academy Press, 1997.

  7. Doig CJ, Rocker G. Retrieving organs from non-heart-beating organ donors: a review of medical and ethical issues. Can J Anaesth 2003;50:1069–1076.

    Article  PubMed  Google Scholar 

  8. Kootstra G, Kievit J, Nederstigt A. Organ donors: heartbeating and non-heartbeating. World J Surg 2002;26:181–184.

    Article  PubMed  Google Scholar 

  9. Cho YW, Terasaki PI, Cecka JM, Gjertson DW. Transplantation of kidneys from donors whose hearts have stopped beating. N Engl J Med 1998;338:221–225.

    Article  PubMed  CAS  Google Scholar 

  10. Weber M, Dindo D, Demartines N, Ambuhl PM, Clavien PA. Kidney transplantation from donors without a heartbeat. N Engl J Med 2002;347:248–255.

    Article  PubMed  Google Scholar 

  11. Steen S, Liao Q, Wierup PN, et al. Transplantation of lungs from non-heart-beating donors after functional assessment ex vivo. Ann Thorac Surg 2003;76:244–252; discussion, 252.

    Article  PubMed  Google Scholar 

  12. Menikoff J. The importance of being dead: non-heart-beating organ donation. Issues Law Med 2002;18:3–20.

    PubMed  Google Scholar 

  13. Youngner SJ, Arnold RM, DeVita MA. When is “dead”? Hastings Cent Rep 1999;29:14–21.

    PubMed  CAS  Google Scholar 

  14. Wijdicks EF, Diringer MN. Electrocardiographic activity after terminal cardiac arrest in neurocatastrophes. Neurology 2004;62:673–674.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Edward M. Manno.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Manno, E.M. Nonheart-beating donation in the neurologically devastated patient. Neurocrit Care 3, 111–114 (2005). https://doi.org/10.1385/NCC:3:2:111

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1385/NCC:3:2:111

Keywords

Navigation