Microangiopathic hemolysis refractory to plasmapheresis responding to docetaxel and cisplatin
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We report the case of a 56-yr-old woman with adenocarcinoma of unknown origin metastatic to the bone marrow presenting with a thrombotic thrombocytopenic purpura-like syndrome refractory to protracted daily plasmapheresis and steroids but readily and completely responsive to docetaxel plus cisplatin. Sustained and complete response was pathologically confirmed.
Key WordsAdenocarcinoma of unknown origin thrombotic thrombocytopenic purpura taxanes cisplatin plasma exchange protein-A immunoadsorption alkylating agents
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