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Use of Radiation Hybrid panels to map genetic loci

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Abstract

The mapping of genetic loci within organisms has been accelerated by the advent of Radiation Hybrid (RH) panels. These panels are available for humans and non-humans including mice, baboon, rat, and canine. This article contains a general protocol for the use of the Genebridge 4 whole genome RH panel to map a human locus. This protocol may also be adjusted to suit the other RH panels currently available.

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Authors and Affiliations

  1. Department of Ophthalmology, University of Alberta, Rm. 832 Medical Sciences Building, T6G-2H7, Edmonton, Alberta, Canada

    James S. Friedman

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  1. James S. Friedman
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  2. Michael A. Walter
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Correspondence to James S. Friedman.

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Friedman, J.S., Walter, M.A. Use of Radiation Hybrid panels to map genetic loci. Mol Biotechnol 19, 205–210 (2001). https://doi.org/10.1385/MB:19:2:205

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  • DOI: https://doi.org/10.1385/MB:19:2:205

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