Skip to main content

Production of the butyrylcholinesterase knockout mouse

This is a preview of subscription content, access via your institution.

References

  • Bartels C. F., Jensen F. S., Lockridge O., van der Spek A. F., Rubinstein H. M., Lubrano T., and La Du B. N. (1992) DNA mutation associated with the human butyryl-cholinesterase K-variant and its linkage to the atypical variant mutation and other polymorphic sites. Am. J. Hum. Genet. 50, 1086–1103.

    PubMed  CAS  Google Scholar 

  • Kalow W. and Gunn D. R. (1957) The relation of between dose of succinylcholine and duration of apnea in man. J. Pharmacol. Exp. Ther. 120, 203–214.

    PubMed  CAS  Google Scholar 

  • Kalow, W. and Gunn, D. R. (1959). Some statistical data on atypical cholinesterase of human serum. Ann. Hum. Genet. 23, 239–250.

    PubMed  CAS  Google Scholar 

  • Liu P., Jenkins N. A., and Copeland N. G. (2003) A highly effencient recombineering-based method for generating conditional knockout mutations. Genome Res. 13, 476–484.

    PubMed  Article  CAS  Google Scholar 

  • Lockridge O. (1990) Genetic variants of human serum cholinesterase influence metabolism of the muscle relaxant succinylcholine. Pharmacol. Ther. 47, 35–60.

    PubMed  Article  CAS  Google Scholar 

  • McGuire M. C., Nogueira C. P., Bartels C. F., Lightstone H., Hajra A., Van der Spek A. F., et al. (1989) Identification of the structural mutation responsible for the dibucaine-resistant (atypical) variant form of human serum cholinesterase. Proc. Natl. Acad. Sci. U.S.A. 86, 953–957.

    PubMed  Article  CAS  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Oksana Lockridge.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Li, B., Duysen, E.G., Saunders, T.L. et al. Production of the butyrylcholinesterase knockout mouse. J Mol Neurosci 30, 193–195 (2006). https://doi.org/10.1385/JMN:30:1:193

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1385/JMN:30:1:193

Keywords

  • Bacterial Artificial Chromosome
  • Homologous Recombination
  • Succinylcholine
  • Thymidine Kinase
  • Bacterial Artificial Chromosome Clone