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Effect of acetylcholine on tau phosphorylation in human neuroblastoma cells

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References

  • Alkondon M., Pereira E. F., Cortes W. S., Maelicke A., and Albuquerque E. X. (1997) Choline is a selective agonist of alpha 7 nicotinic acetylcholine receptors in rat brain neurons. Eur. J. Neurosci. 9, 2734–2742.

    PubMed  Article  CAS  Google Scholar 

  • Ávila, J., Lucas, J. J., Pérez, M., and Hernández, F. (2004) Role of tau protein in both physiological and pathological conditions. Physiol. Rev. 84, 361–384.

    PubMed  Article  Google Scholar 

  • Biedler, J. L., Roffler-Tarlw, S., Schachner M., and Freedman L. S. (1978) Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones. Cancer Res. 38, 3751–3757.

    PubMed  CAS  Google Scholar 

  • Bowen D. M., Smith C. B., White, P., and Davison, A. N. (1976) Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies. Brain 99, 459–496.

    PubMed  Article  CAS  Google Scholar 

  • Davies, P. and Maloney A. J. (1976) Selective loss of central cholinergic neurons in Alzheimer's disease. Lancet, 25, 1403.

    Article  Google Scholar 

  • Feijoo C., Campbell D. G., Jakes R., Goedert M., and Cuenda A. (2004) Evidence that phosphorylation of the microtubule-associated protein Tau by SAPK4/p38delta at Thr50 promotes microtubule assembly. J. Cell Sci. 118, 387–408.

    Google Scholar 

  • Novak M., Jakes R., Edwards P. C., Milstein C., and Wischik C. M. (1991) Difference between the tau protein of Alzheimer paired helical filament core and normal tau revealed by epitope analysis of monoclonal antibodies 423 and 7.51. Proc. Natl. Acad. Sci. U. S. A. 88, 5837–5841.

    PubMed  Article  CAS  Google Scholar 

  • Pérez, M., Hernández, F., Gómez-Ramos A., Smith M., Perry G., and Ávila, J. (2002) Formation of aberrant phosphotaupolymers in neural cultured cells. Eur. J. Biochem. 269, 1484–1489.

    PubMed  Article  Google Scholar 

  • Perry E. K., Blessed G., Tomlinson B. E., Perry R. H., Crow T. J., Cross, A. J., et al. (1981) Neurochemical activities in human temporallobe related to aging and Alzheimer-type changes. Neurobiol. Aging, 2, 251–256.

    PubMed  Article  CAS  Google Scholar 

  • Seubert P., Mawal-Dewan M., Barbour R., Jakes R., Goedert M., Johnson G. V., et al. (1995) Detection, of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament taul. J. Biol. Chem. 270, 18,917–18,922.

    CAS  Google Scholar 

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Rubio, A., Ávila, J. & Pérez, M. Effect of acetylcholine on tau phosphorylation in human neuroblastoma cells. J Mol Neurosci 30, 185–188 (2006). https://doi.org/10.1385/JMN:30:1:185

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  • DOI: https://doi.org/10.1385/JMN:30:1:185

Keywords

  • Molecular Neuroscience Volume
  • Human Neuroblastoma Cell
  • 12E8 Antibody
  • Human Neuroblastoma Cell Line
  • Alpha7 Nicotinic Acetylcholine Receptor