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Long-term results after surgery for gastric cancer with or without jejunal reservoir

Results of surgery for gastric cancer in kanta-häme central hospital in two consecutive periods without or with jejunal pouch reconstruction in 1985–1998

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Abstract

Background: Gastric cancer still has a disease-specific 5-yr survival less than 30% and an overall survival of about 15%. The quality of life of patients who undergo gastrectomy is poor owing both to the severity of the disease itself and to the mutilation of the upper gastrointestinal channel after the reconstruction. Therefore, the combination of a jejunal pouch with gastrectomy has been claimed to improve the life quality and nutritional status of these patients.

Aim: To assess the clinical results after surgery for gastric cancer in two consecutive periods with or without jejunal-pouch reconstruction.

Methods: 271 consecutive patients referred for surgery for gastric cancer in 1985–1991 (116 patients) and in 1992–1998 (155 patients) in Kanta-Häme central hospital were retrospectively analyzed regarding their disease, mode of surgery, and the immediate and long-term results. In the former observation period gastrectomy was performed with Roux-en-Y esophagojejunostomy without a reservoir, and in the latter period this procedure was combined with a jejunal reservoir. The data were collected from patient journals and from the death certificate obtained from the National Centre of Statistics in Finland.

Results: During the study period the incidence of cancer in the cardia increased among the surgical patients from 13.1 to 26.7% (p <0.05). Despite this proximal migration, the cancer-specific 5-yr survival remained practically unchanged during the two study periods, 29.4% and 32.2% (NS). During the period of jejunal-pouch reconstruction there were non-significant increases of the incidences of local recurrence (from 18.9% to 26.5%), of immediate postoperative anastomotic fistulae (from 0.9% to 4.5%) as well as of the immediate mortality (from 2.6% to 3.7%) (NS for each).

Conclusions: Despite proximal migration of gastric cancer and the application of a jejunal reservoir, the long-term as well as the immediate results after curative surgery (i.e., D2-gastrectomy) for gastric cancer have remained relatively unchanged. The jejunal-pouch reconstruction with the present technique after gastrectomy can therefore be safely applied.

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Authors and Affiliations

  1. Department of Surgery, Narvik Hospital, PB: 273, 8504, Narvik, Norway

    Hannu Paimela MD, PhD

  2. Department of Surgery, Tempere University Hospital, Tampere

    Saara Ketola & Niku Oksala

  3. Department of Surgery, Kanta-Häme Central Hospital, Hämeenlinna

    Timo Tomminen & Esa Könönen

  4. Department of Surgery, Forssa Hospital, Forssa

    Mauri Iivonen

  5. Department of Surgery, Helsinki University Hospital, Helsinki, Finland

    Harri Mustonen

Authors
  1. Hannu Paimela MD, PhD
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  2. Saara Ketola
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  3. Mauri Iivonen
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  4. Timo Tomminen
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  5. Esa Könönen
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  6. Niku Oksala
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  7. Harri Mustonen
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Correspondence to Hannu Paimela MD, PhD.

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Paimela, H., Ketola, S., Iivonen, M. et al. Long-term results after surgery for gastric cancer with or without jejunal reservoir. Int J Gastrointest Canc 36, 147–153 (2005). https://doi.org/10.1385/IJGC:36:3:147

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