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Primary malignant fibrous histiocytoma of the small bowel

A report of an additional case in duodenum

  • Case Report
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Abstract

Aims: We report herein an additional case of primary malignant fibrous histiocytoma (MFH) in the duodenum and provide a review of the existing literature.

Methods and Results: A 61-yr-old Chinese man was admitted to our hospital with symptoms of melena, anorexia, and weight loss. An abdominal computed tomography (CT) and gastrointestinal barium meal examination demonstrated a tumor of the duodenum suggestive of primary malignancy. The tumor was successfully treated by pancreaticoduodenectomy. It was histopathologically and immunohistochemically diagnosed to be a storiform-type primary MFH of the duodenum. There have been a total of 40 cases of primary malignant fibrous histiocytoma of the small bowel documented in the literature including our Chinese cases.

Conclusion: Primary malignant fibrous histiocytoma of the small bowel, especially in the duodenum is extremely rare. The final diagnosis is made only after pathological and immunopathological examination of the tumor. The malignant potential of such tumors is high. The prognosis may be mainly dependent on the invasion and metastasis of tumor, while tumor size is irrelevant. The treatment should be surgery if possible. Early surgical intervention may be the best form of management that may offer the patient good result.

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References

  1. Cormier JN, Pearson AS, Meterissian SH, Tanabe KK. Bone and soft tissue sarcoma, in The M.D. Anderson Surgical Oncology Handbook. (Feig BW, Berger DH, Fuhrman GM, eds.) Philadelphia, PA: Lippincott Williams & Wilkins, 2003; pp. 87–108.

    Google Scholar 

  2. Ros PR, Viamonte M Jr, Rywein AM. Malignant fibrous histiocytoma: mesenchymal tumor of ubiquitous origin. AJR Am J Roentgenol 1984;142:753–759.

    PubMed  CAS  Google Scholar 

  3. Conlon KC, Casper ES, Brennan MF. Primary gastrointestinal sarcoma: analysis of prognostic variables. Ann Surg Oncol 1995;2:26–31.

    Article  PubMed  CAS  Google Scholar 

  4. Farinon AM, Bock E, Federico F, D’Antini P. Primary malignant fibrous histiocytoma of the duodenum. Dig Surg 1999;16(5):425–430.

    Article  PubMed  CAS  Google Scholar 

  5. Gill SS, Heuman DM, Mihas AA. Small intestinal neoplasms. J Clin Gastroenterol 2001;33:267–282.

    Article  PubMed  CAS  Google Scholar 

  6. Peiper M, Zurakowski D, Knoefel WT, Izblckki JR. Malignant fibrous histiocytoma of the extremities and trunk: an institutional review. Surgery 2004;135:59–66.

    Article  PubMed  Google Scholar 

  7. Wiersema AM, Wobbes TH, Pruszczynski M, Van der Sluis RF. Malignant fibrous histiocytoma of the stomach during pregnancy:a case report. Euro J Obstet Gynecol Reprod Biol 1998;80(3):71–73.

    Article  CAS  Google Scholar 

  8. Leite C, Goodwin JW, Sinkovics FG, Baker LH, Benjamen R. Chemotherapy of malignant fibrous histiocytoma: a Southwest Oncology Group report. Cancer 1977;40:2010–2014.

    Article  PubMed  CAS  Google Scholar 

  9. Fujita A, Isai H, Kondo M, Minase T, Tagaki S, Sekine K. A case of malignant fibrous histiocytoma of jejunal origin with marked response to cisplatin, ifosfamide and adriamycin (in Japanese with English abstract). Jpn J Cancer Chemother 1993;20:2053–2056.

    CAS  Google Scholar 

  10. Hanaoka T, Suzuki E, Fujii T, Takahashi H, Ishida K, Mihara Y. A case of malignant fibrous histiocytoma of the ileum (in Japanese with English abstract). J Jpn Surg Assoc 2000;61:986–990.

    Google Scholar 

  11. Lin JI, Kim KC, Tsung SH, Peoples JB. Malignant fibrous histiocytoma of the ileum. Dis Colon Rectum 1983;26:335–338.

    Article  PubMed  CAS  Google Scholar 

  12. Singh G, Gupta S. Malignant fibrous histiocytoma of solitary jejunal diverticulum. J Surg Oncol 1985;28:273–276.

    Article  PubMed  CAS  Google Scholar 

  13. Shibuya H, Azumi N, Onda Y, Abe F. Multiple primary malignant fibrous histiocytoma of the stomach and intestine (in Japanese with English abstract). Acta Pathol Jpn 1985;35:157–164.

    PubMed  CAS  Google Scholar 

  14. Gilman JK, Sievers DB, Thornsvard CT. Malignant fibrous histiocytoma manifesting as a cavitary lung metastasis. South Med J 1986;79:376–378.

    Article  PubMed  CAS  Google Scholar 

  15. Sakoh M, Saito M, Waseda M, et al. A case of malignant fibrous histiocytoma of the ileocecal region (in Japanese with English abstract). Yokohama Igaku 1996;47:585–590.

    Google Scholar 

  16. Kobayashi K, Narita H, Morimoto K, Hato M, Ito A, Sugyama K. Primary malignant fibrous histiocytoma of the ileum: report of a case. Surg Today 2001;31:727–731.

    Article  PubMed  CAS  Google Scholar 

  17. Cordoba Diaz de Laspra E, Calleja JL, Hernando E, Lahuerta L. Primary malignant fibrous histiocytoma of the jejunum: report of a case and rview of subject. J R Coll Surg Edinb 1997;42:355–358.

    PubMed  CAS  Google Scholar 

  18. Fukunaga M, Endo Y, Ushigome S. Radiation-induced inflammatory malignant fibrous histiocytoma of the ileum. APMIS 1999;107:837–842.

    Article  PubMed  CAS  Google Scholar 

  19. Rasero M, Manjon AP, Jimenez M. Malignant fibrous histiocytoma of the ileum. Eur Radiol 1999;9:1236–1237.

    Article  PubMed  CAS  Google Scholar 

  20. Umehara M, Watanabe A, Matsumoto S, Saito T, Naito Z. G-CSF producing malignant fibrous histiocytoma in the jejunum: a case report. Hepatogastroenterology 2000;47:1630–1632.

    PubMed  CAS  Google Scholar 

  21. Froehner M, Gaertner HJ, Hakenberg OW, Wirth MP. Malignant fibrous histiocytoma of the ileum at a site of previous surgery: report of a case. Surg Today 2001;31:242–245.

    Article  PubMed  CAS  Google Scholar 

  22. Atmatzidis KS, Pavlidis TE, Galanis IN, Papaziogas BT, Papaziogas TB. Malignant fibrous histiocytoma of the abdominal cavity: report of a case. Surg Today 2003;33:794–796.

    Article  PubMed  Google Scholar 

  23. Zhong CH, Lu HM, Zhang ZD, Li DG. Xiao chang duo fa xing e’xing xian wei zu zhi xi bao liu ban chu xue chuang kong yi li (in Chinese with no English abstract). Chin J Dig 2001;21:543.

    Google Scholar 

  24. Xu YM, Wu PJ, Wu WH, Chen HX. Xiao chang e’xing xian wei zu zhi xi bao liu yi li (in Chinese with no English abstract). Chin J Gen Surg 2002;17:751.

    Google Scholar 

  25. Jiao YE, Nakamura S, Sugai T, et al. P53 gene mutation and MDM2 overexpression in a case of primary malignant fibrous histiocytoma of the jejunum. APMIS 2002;110:165–171.

    Article  PubMed  CAS  Google Scholar 

  26. Kotan C, Kosem M, Alici S, Ilhan M, Tuncer I, Harman M. Primary malignant fibrous histiocytoma of the small intestine presenting as an intussusception: report of a case. Surg Today 2002;32:1091–1095.

    Article  PubMed  Google Scholar 

  27. Carip C, de Beaumont T. Malignant fibrous histiocytoma of the small intestine in a young immune deficient patient (in French with English abstract). Presse Med 2002;31:214–216.

    PubMed  CAS  Google Scholar 

  28. Spanos C, Trigonis S, Aggelidou S, Efstration I, Kiskinis D, Syrrakos T. Primary malignant fibrous histiocytoma of the junum metastatic to the spine: report of a case. Int J Gastrointest Cancer 2005;35:143–145.

    Article  PubMed  Google Scholar 

  29. Zhang YJ, Li WL, Wang C, Zhang LY. Yuan fa xing xiao chang e’xing xian wei zu zhi xi bao liu yi li (in Chinese with no English abstract). Chin J Clin Oncol 2004;31:130.

    Google Scholar 

  30. Ryu U, Lim BW, Roh JW, et al. Primary malignant fibrous histiocytoma (MFH) of the small bowel presenting as an intussusception causing small bowel obstruction (in Korean with English abstract). Korean J Gastroenterol 2004;44:99–102.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Pathology, Renmin Hospital of Wuhan University, 238 Jiefang Road, 430060, Wuhan, MN, China

    Ze-sheng Wang MD, Na Zhan, Guo-sheng Xiong, Hui Li & Hong Hu

  2. Department of Surgery, Renmin Hospital of Wuhan University, 238 Jiefang Road, 430060, Wuhan, MN, China

    Cheng-long Xiong

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  1. Ze-sheng Wang MD
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  2. Cheng-long Xiong
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  3. Na Zhan
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  4. Guo-sheng Xiong
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  5. Hui Li
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Correspondence to Ze-sheng Wang MD.

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Wang, Zs., Xiong, Cl., Zhan, N. et al. Primary malignant fibrous histiocytoma of the small bowel. Int J Gastrointest Canc 36, 105–112 (2005). https://doi.org/10.1385/IJGC:36:2:105

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