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HPV-associated carcinoma of esophagus in the young

A case report and review of literature

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Abstract

Esophageal carcinoma (EC) is rare in the younger age group, with only 15 cases reported in world literature. It is even rarer for an etiological agent to be implicated.

A case of a 15-yr-old boy with squamous cell carcinoma of the esophagus is reported. Human papillomavirus (HPV) 16 DNA sequences were detected in the neoplasm and the adjacent mucosa by polymerase chain reaction followed by restriction fragment length polymorphism (PCR-RFLP). The adjacent mucosa also showed virus-induced changes.

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Authors and Affiliations

  1. Department of Pathology, Lilavati Hospital and Research Centre Mumbai, India

    Chandralekha Tampi MD, Sandhya Pai & Vatsala M. Doctor

  2. Department of Gastroenterology, Lilavati Hospital and Research Centre Mumbai, India

    S. Plumber

  3. Department of Surgical Oncology, Lilavati Hospital and Research Centre Mumbai, India

    P. Jagannath

Authors
  1. Chandralekha Tampi MD
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  2. Sandhya Pai
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  3. Vatsala M. Doctor
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  4. S. Plumber
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  5. P. Jagannath
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Correspondence to Chandralekha Tampi MD.

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Tampi, C., Pai, S., Doctor, V.M. et al. HPV-associated carcinoma of esophagus in the young. Int J Gastrointest Canc 35, 135–142 (2005). https://doi.org/10.1385/IJGC:35:2:135

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