Conclusions
Immunotherapy continues to be an important component in the treatment of allergic diseases. It remains the only mode of treatment that has exhibited the potential for modifying the natural history of allergic diseases and possibly for preventing them from occurring at all. Though many aspects of its administration still need to be studied in a scientifically rigorous manner, it has proven to be effective even when given with nonstandardized methods. As a result, it continues to be important for physicians to learn the art of giving effective immunotherapy in addition to the ever-expanding science.
Similar content being viewed by others
References
Noon, L. (1911), Lancet i, 1572–1573.
Bousquet, J., Hejjaoui, A., and Michel, F. (1990), J. Allergy Clin. Immunol. 86 (3 Pt 1), 292–305.
Abramson, M., Puy, R., and Weiner, J. (1995), Am. J. Respir. Crit. Care Med. 151, 969–974.
Ross, R., Nelson, H., and Finegold, I. (2000), Clin. Therapeut. 22(3), 329–341.
Ross, R., Nelson, H., and Finegold, I. (2000), Clin. Therapeut. 22(3), 342–350.
Turkeltaub, P. (1999), Allergen vaccine unitage based on biological standardization: clinical significance, in Allergens and Allergen Immunotherapy, 2nd ed. Lockey, R. and Bukantz, S., eds., Marcel Dekker, Inc., New York, pp. 321–340.
Nelson, H. (1981), J. Allergy Clin. Immunol. 67, 64–69.
Hjorth, N. (1958), Acta Allergol, 12, 316–335.
Lowell, F. and Franklin, W. (1965), N. Engl. J. Med. 675–679.
Weber, R. and Nelson, H. (1985), Clin. Rev. Allergy, 3, 291–318.
Esch, R. (1991), Arb Paul Ehrlich Institut, 85, 171–179.
Nelson, H., Ikle, D., and Buchmeier, A. (1996), J. Allergy. Clin. Immunol. 98, 382–388.
Sharkey, P. and Portnoy, J. (1996), Ann. Allergy Asthma Immunol. 76(2), 175–180.
Bernstein, J., Kagen, S., Bernstein, D., and Bernstein, I. (1994), Ann. Allergy, 73, 423–428.
Portnoy, J., King, K., Kanarek, H., and Horner, S. (1992), Ann. Allergy, 68 (6), 493–498.
Portnoy, J., King, K., and Kanarek, H. (1994), Ann. Allergy 73(5) 409–418.
Gleich, G., Zimmermann, E., Henderson, L., et al. (1982), J. Allergy. Clin. Immunol. 70, 261–271.
Peng, Z., Naclerio, R., Norman, P., et al. (1992), J. Allergy. Clin. Immunol. 89, 519–529.
Sadan, N., Rhyne, M., Mellits, E., et al. (1969), N. Engl. J. Med. 280, 623–627.
Lichtenstein, L. and Levy, D. (1972), Int. Arch. Allergy Appl. Immunol. 42, 615–626.
Bonno, M., Fujisawa, T., Iguchi, K., et al. (1996), J. Allergy Clin. Immunol. 97, 680–688.
Lkajaic-Turkalj, M., Cvoriscec, B., Tudoric, N., et al. (1996), Int. Arch. Allergy Appl. Immunol. 111, 188–194.
Wang, J-Y., Lei, H-Y., and Hsieh, K-H. (1992), J. Asthma, 29, 193–201.
Varney, V., Hamid, Q., Gaga, M., et al. (1993), J. Clin. Invest. 92, 644–651.
Ohman, J.J., Findlay, S., and Leitermann, K. (1984), J. Allergy Clin. Immunol. 74(3 Pt 1), 230–209.
Bousquet, J., Maasch, H., Martinot, B., et al. (1988), J. Allergy Clin. Immunol. 82, 439–446.
Lofkvist, T., Agrell, B., Dreborg, S., et al. (1994), Allergy, 152, 100–107.
Durham, S., Walker, S., Varga, E., Jacobson, M., O'Brien F., Noble, W., et al. (1999), N. Engl. J. Med. 341(7), 468–475.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Portnoy, J.M. Immunotherapy for allergic diseases. Clinic Rev Allerg Immunol 21, 241–259 (2001). https://doi.org/10.1385/CRIAI:21:2-3:241
Issue Date:
DOI: https://doi.org/10.1385/CRIAI:21:2-3:241