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Accumulation of elements in the arteries and cardiac valves of Thai with aging

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Abstract

To elucidate whether the extent of element accumulation in the arteries and cardiac valves with aging was different between different races, the authors investigated the accumulation of elements in the arteries and cardiac valves of the Thai with aging and the relationships among elements in the cardiac valves. After ordinary dissection at Chiang Mai University was finished, 16 arteries and 4 cardiac valves were resected and element contents were determined by inductively coupled plasma-atomic emission spectrometry.

In the 16 arteries, the average content of calcium was the highest in the site of the abdominal aorta ramifying into the common iliac arteries, and it decreased in the order internal iliac, coronary, abdominal aorta, common iliac, external iliac, superior mesenteric, inferior mesenteric, thoracic aorta, brachial, radial, common carotid, subclavian, ulnar, axillary, renal, and internal thoracic arteries. The average contents of phosphorus and magnesium in respective arteries were parallel with the average contents of calcium, except for the coronary artery. In comparison with the arteries of the Japanese, the trend of calcium accumulation in the arteries of the Thai was almost similar to that in the arteries of the Japanese, except for the coronary artery and thoracic aorta. The calcium accumulation in the coronary artery was much higher in the Thai than in the Japanese, whereas that in the thoracic aorta was lower in the Thai than in the Japanese.

Regarding elements in the cardiac valves, the calcium content increased remarkably in the seventies in the aortic valve and in the nineties in the pulmonary valve, but it hardly increased in both the mitral and tricuspid valves with aging. The average content of calcium was the highest in the aortic valve, and it decreased in the order pulmonary, tricuspid, and mitral valves. Regarding the relationship among elements in the aortic valves, it was found that there were extremely significant direct correlations among the contents of calcium, phosphorus, and magnesium, whereas there were significant direct correlations between zinc and either calcium or phosphorus contents. Although significant correlations were found between sulfur and the other element contents in the aortic valves of the Japanese, no significant correlations were found between them in the aortic valves of the Thai. In the mitral valves, extremely or very significant direct correlations were found among the contents of calcium, phosphorus, magnesium, and sulfur, with some exceptions that there were no significant correlations between phosphorus and either magnesium or sulfur contents.

In addition, no significant correlation was found in the calcium content between the aortic valve and coronary artery in the same individuals.

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Authors and Affiliations

  1. Laboratory of Cell Biology, Department of Anatomy, Nara Medical University, Kashihara, 634-8521, Nara, Japan

    Yoshiaki Ohnishi, Setsuko Tohno, Yoshiyuki Tohno, Cho Azuma & Yumi Moriwake

  2. Department of Pharmacology, Nara Medical University, Kashihara, 634-8521, Nara, Japan

    Hiroyasu Satoh

  3. Department of Anatomy, Faculty of Medicine, Chiang Mai University, 50200, Chiang Mai, Thailand

    Pasuk Mahakkanukrauh, Pidhyasak Vaidhayakarn & Ranida Chomsung

  4. Laboratory of Environmental Biology, Department of Life Science, Faculty of Science and Engineering, Kinki University, Higashi-Osaka, 577-8502, Osaka, Japan

    Takeshi Minami

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Ohnishi, Y., Tohno, S., Mahakkanukrauh, P. et al. Accumulation of elements in the arteries and cardiac valves of Thai with aging. Biol Trace Elem Res 96, 71–92 (2003). https://doi.org/10.1385/BTER:96:1-3:71

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  • DOI: https://doi.org/10.1385/BTER:96:1-3:71

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