Abstract
This study was carried out to evaluate the effects of chronic fluorosis by means of the electrocardiograms in sheep. Ten sheep with fluorosis living around a volcanic mountain (Tendürek Mount) in East Anatolia in Turkey and 10 healthy sheep were used. Leads I, II, III, aVR, aVL, aVF, V2, V4, and V10 were recorded in the electrocardiographs of the sheep. All waves were seen in all derivations. The P-Q interval was significantly (p<0.05) prolonged and sinus bradycardia was observed in the sheep with fluorosis. As a result of this, the number of heart beats was decreased significantly (p<0.05); that is, the number of heart beats was 110±15 in the control group and 75±10 in sheep with fluorosis.
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References
H. Rubin Carol and K. Noji Eric, Evaluating a fluorosis hazard after a volcanic eruption, Arch. Environ. Health 49(5), 395–403 (1994).
I. E. Coop, Sheep and Goat Production. World Animal Science, Cl., New York (1982).
WHO, Fluorides and Oral Health. Report of WHO Expert Committee on Oral Health Status and Fluoride Use, WHO, Geneva (1994).
H. S. Ergün, H. A. Rüssel-Sinn, N. Bayşu, et al., Studies on the fluoride contents in water and soil. Urine, bone and teeth of sheep and urine of human from eastern and western parts of Turkey, DTW 94, 416–420 (1987).
K. N. Burns and R. Allcroft, Fluorosis, Vet. Rec. 76(18), 507–509 (1964).
I. D. Brouwer, O. Bockerdirks, A. Debruin, et al., Unsuitability of world health organization guidelines for fluoride concentrations in drinking water in Senegal, Lancet 30, 223–225 (1988).
S. L. Choubisa, Some observations on endemic fluorosis in domestic animals in Southern Rajasthan (India), Vet. Res. Commun. 23, 457–465 (1999).
A. Bildik, Florozisli koyunlarda kan serumundaki iyot değerleri ile bazı spesifik karaciğer enzim aktivitelerinin araştırılması, PhD thesis, Yüzüncü Yil University, Van, Turkey (1992).
N. Maraşlı, Research on the levels triiodothyronine (T3) and thyroxine (T4) in normal sheep and sheep with fluorosis, PhD thesis. Ankara University, Ankara (1991).
T. Sel, Serum levels of specific liver enzymes (glutamate oxalacetate transaminase, glutamate pyruvate transaminase, lactate dehydrogenase) and alkaline phosphatase in normal sheep and sheep showing sings of fluorosis in Eastern Anatolia, PhD thesis, Ankara University, Ankara (1991).
B. Yılmaz, Physiology, Feryal Matbaacılık. Ankara (2000).
T. Konuk, Practise Physiology, A. Ü. Vet. Fak. Yayınları. Ankara (1981).
G. Zhi-zhong, J. Zong, Y. Pei Shei, et al., Synergistic action of iodine. Deficiency and fluorine-intoxication on rat thyroid, Chin. Med. J. 101(9), 679–684 (1988).
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Dönmez, N., Çinar, A. Effects of chronic fluorosis on electrocardiogram in sheep. Biol Trace Elem Res 92, 115–121 (2003). https://doi.org/10.1385/BTER:92:2:115
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DOI: https://doi.org/10.1385/BTER:92:2:115