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Determination of urinary beryllium, arsenic, and selenium in steel production workers

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Abstract

Some of the most pernicious dangers of pollution arise from the presence of traces of toxic elements in the environment. In this work, we report on the determination of beryllium, arsenic, and selenium in the urine of steel production and steel quality control (QC) workers, in comparison to healthy control subjects. The urine samples were digested by a microwave system. Graphite furnace and hydride atomic absorption was used for the quantitative measurements of Be and As and Se, respectively. A quality control method for these procedures was established with concurrent analysis of Standard Trace Metals 7879 Level II and NIST SRM 2670 (Toxic Elements in Freeze Dried Urine).

The results show that the urinary levels of these elements in steel production (As, 38.1±28.7 µg/L; Be, 1.58±0.46 µg/L, and Se, 69.2±28.8µg/L) and in quality control workers (As, 23.9±18.1 µg/L; Be, 1.58±0.46 µg/L, and Se, 54.8±25.1 µg/L) are significantly higher than in the controls (As, 10.3±8.7 µg/L; Be, 0.83±0.46 µg/L; and Se, 32.3±13.5 µg/L).

The possible connection of these elements with the etiology of disease and the possible role of selenium as a protective agent against the oncogenic and teratogenic action of other substances is discussed. We suggest the need for improvement of environmental conditions in the workplace through better ventilation and industrial hygiene practices.

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References

  1. A. M. Bond and J. B. Reust, Anal. Chim. Acta 162, 389–392 (1984).

    Article  CAS  Google Scholar 

  2. J. A. Fiorino, J. W. Jones, and S. G. Capar, Anal. Chem. 48, 120–125 (1976).

    Article  PubMed  CAS  Google Scholar 

  3. B. Welz and M. Melcher, Atomic Absorpt Newslett 18, 121–122 (1979).

    CAS  Google Scholar 

  4. R. C. Chu, G. P. Barron, and P. A. W. Baumgarner, Anal. Chem. 44, 1476–1479 (1972).

    Article  CAS  Google Scholar 

  5. C. J. Horng and S. R. Lin, Biol. Trace Element Res. 55, 307–314 (1996).

    Google Scholar 

  6. C. J. Horng, J. L. Tsai, and S. R. Lin, Biol. Trace Element Res. 70(1), 29–40 (1999).

    CAS  Google Scholar 

  7. L. Fishbein, Int. J. Environ. Anal. Chem. 17, 113–170 (1984).

    PubMed  CAS  Google Scholar 

  8. D. A. Lytle, M. R. Schock, N. R. Dues, and J. U. Doerger, J. Am. Water Works Ass. 85(2), 77–83 (1993).

    CAS  Google Scholar 

  9. C. J. Horng, Analyst 121, 1511–1514 (1996).

    Article  Google Scholar 

  10. M. Vahter, Acta Pharm. Toxicol. 59(Suppl. 7), 31–34 (1986).

    CAS  Google Scholar 

  11. V. Bencko and K. Symon, Environ. Res. 13, 378–385 (1977).

    Article  PubMed  CAS  Google Scholar 

  12. M. Stoeppler and M. Apel, Fresenius Z. Anal. Chem. 317, 226–227 (1984).

    Article  CAS  Google Scholar 

  13. H. Yamachi, K. Takahashi, M. Mashiko, and Y. Yamamura, Am. Ind. Assoc. J. 50, 606–612 (1989).

    Google Scholar 

  14. T. C. Pan and C. W. Huang, Am. Ind. Hyg. Assoc. J. 54, 454–457 (1993).

    CAS  Google Scholar 

  15. D. L. Tsalev and Z. K. Zaprianov, Atomic Absorption Spectrometry in Occupational and Environmental Health Practice, Volume I. CRC Press, Boca Raton, FL, pp. 13–178 (1985).

    Google Scholar 

  16. J. A. Vale and T. J. Mereditle, A concise Guide to the Management of Poisoning, 3rd ed., Churchill Livingstone, Edinburgh, pp. 39–40 (1985).

    Google Scholar 

  17. O. Neubaber, Arsenïcal cancer: a review. Br. J. Cancer 1 192–251 (1947).

    Google Scholar 

  18. G. D. Clayton and F. E. Clayton, Patty’s Industrial Hygiene and Toxicology, Volume 2A, Toxicology, 3rd rev. ed., Wiley, Chichester, pp. 1517–1531 (1981).

    Google Scholar 

  19. Finkel A. J. Hamilton and Hardy’s Industrial Toxicology, 4th ed., Boston, John Wright PSG Inc., pp. 17–103 (1983).

    Google Scholar 

  20. D. S. Grewal and K. X. Kearns, A simple and rapid determination of small amounts of Be in urine by flameless AA, Atomic Absorpt. Newslett. 16, 131 (1977).

    CAS  Google Scholar 

  21. T. Stiefel, K. Schulze, H. Zorn, and G. Tolg, Arch. Toxicol. 45, 89–92 (1980).

    Article  Google Scholar 

  22. IARC, IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Some Metals and Metallic Compounds, Volume 23, International Agency for Research on Cancer, Lyon (1980).

    Google Scholar 

  23. D. C. Paschal and G. G. Bailey, Atomic Spectrosc. 7, 1–3 (1986).

    CAS  Google Scholar 

  24. J. J. Dulka and T. H. Risby, Ultratrace metals in some environmental and biological systems, Anal. Chem. 48, 640A-653A (1976).

    Article  PubMed  CAS  Google Scholar 

  25. M. M. Kimberly and D. C. Paschal, Anal. Chim. Acta 174, 203–210 (1985).

    Article  CAS  Google Scholar 

  26. J. L. Valentine, B. Faraji, and H. K. Kang, Environ. Res. 45, 16–27 (1988).

    Article  PubMed  CAS  Google Scholar 

  27. P. B. Cadell and F. B. Cousins, Nature 185, 863–864 (1960).

    Article  PubMed  CAS  Google Scholar 

  28. J. R. Glover, Ann. Occup. Hyg. 10, 3–14 (1967).

    PubMed  CAS  Google Scholar 

  29. Hojo Y. Bull, Subject groups high and low in urinary selenium levels: workers exposed to heavy metals and patients with cancer and epilepsy. Environ. Contam. Toxicol. 26, 466–471 (1981).

    Article  Google Scholar 

  30. G. N. Schrauzer, Sangyo Ika Daigaku Zasshi 9(Suppl. 208–215) 20 (1987).

    Google Scholar 

  31. L. Gerhardsson, D. Brune, I. G. F. Nordberg, and P. O. Wester, Br. J. Ind. Med. 42, 617–626 (1984).

    Google Scholar 

  32. G. D. Clayton and F. E. Clayton, Patty’s Industrial Hygiene and Toxicology, Volume 2A, Toxicology, 3rd rev. ed., J Wiley, pp. 2130–2135 (1981).

  33. P. O. Wester, D. Brune, and G. Nordberg, Br. J. Ind. Med. 38, 179–184 (1981).

    PubMed  CAS  Google Scholar 

  34. C. J. Horng and S. R. Lin, Talanta 45, 75–83 (1997).

    Article  CAS  Google Scholar 

  35. H. J. Robberecht and H. A. Deelstra, Talanta 31, 497 (1984).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. School of Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan, 80708, Republic of China

    C. J. Horng, P. H. Horng, S. C. Lin, S. R. Lin & C. C. Tzeng

  2. Graduate Institute of Occupational Safety, Kaohsiung Medical University, Kaohsiung, Taiwan, 80708, Republic of China

    J. L. Tsai

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Horng, C.J., Horng, P.H., Lin, S.C. et al. Determination of urinary beryllium, arsenic, and selenium in steel production workers. Biol Trace Elem Res 88, 235–246 (2002). https://doi.org/10.1385/BTER:88:3:235

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  • DOI: https://doi.org/10.1385/BTER:88:3:235

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