Biological Trace Element Research

, Volume 77, Issue 3, pp 193–197 | Cite as

Selenium, boron, and germanium deficiency in the etiology of Kashin-Beck disease

  • Xu Peng
  • Zeng Lingxia
  • G. N. Schrauzer
  • Guo Xiong


Concentrations of selenium (Se), boron (B), and germanium (Ge) were determined in scalp hair of children with Kashin-Beck disease (KBD), in healthy children in KBD-disease endemic areas, and in healthy children in non-KBD areas. Mean Se, B, and Ge concentrations were low in children with KBD; in hair of healthy children in KBD areas, Se levels were normal but B and Ge levels were lower than in KBD-free areas. The hair levels of B and Ge were unaffected by selenium supplementation. It is suggested that B and Ge deficiency may be contributing factors in the etiology of KBD.

Index Entries

Kashin-Beck disease scalp hair boron germanium selenium 


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Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • Xu Peng
    • 1
  • Zeng Lingxia
    • 1
  • G. N. Schrauzer
    • 2
  • Guo Xiong
    • 1
  1. 1.Institute of Endemic Bone DiseasesXi’an Medical UniversityXi’anP. R. China
  2. 2.Biological Trace Element Research InstituteSan Diego

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