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Decreases of calcium and phosphorus in monkey cardiac walls with development and aging

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Abstract

To elucidate compositional changes of the cardiac walls with development and aging, the authors investigated changes of elements in the atrial and ventricular walls of monkeys. The left and right atrial walls, left and right ventricular walls, and interatrial and interventricular septa were resected from the subjects. The subjects consisted of 17 rhesus and 13 Japanese monkeys, ranging in age from 10 d to 33 yr. The element content of the cardiac walls was analyzed by inductively coupled plasma-atomic emission spectrometry. The Ca and P contents decreased in all of the left and right atrial and ventricular walls, interatrial septa, and interventricular septa with development, whereas the S and Mg contents decreased in the left and right ventricular walls with development. Regarding the relationships among elements, significant direct correlations were found among Ca, P, Mg, and Zn in all of the left and right atrial walls, left and right ventricular walls, and interatrial and interventricular septa, with some exceptions. As Ca decresed in the cardic walls, P, Mg, and Zn decreased simultaneously in the cardiac walls. The mass ratio of Ca/P decreased gradually with Ca decrease in both the atrial and ventricular walls, but it was not constant.

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Authors and Affiliations

  1. Laboratory of Cell Biology, Department of Anatomy, Nara Medical University School of Medicine, Kashihara, 634-8521, Nara, Japan

    Setsuko Tohno, Yoshiyuki Tohno, Cho Azuma & Yumi Moriwake

  2. Department of Pharmacology, Nara Medical University School of Medicine, Kashihara, 634-8521, Nara, Japan

    Hiroyasu Satoh

  3. Laboratory of Environmental Biology, Department of Life Science, Faculty of Science and Engineering, Kinki University, Higashi-Osaka, 577-8502, Osaka, Japan

    Takeshi Minami

  4. Department of Anatomy, Faculty of Medicine, Chiang Mai University, 50200, Chiang Mai, Thailand

    Pasuk Mahakkanukrauh

  5. Department of Cellular and Molecular Biology, Primate Research Institute, Kyoto University, 484-8506, Inuyama, Aichi, Japan

    Takao Ohishi & Motoharu Hayashi

Authors
  1. Setsuko Tohno
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  2. Yoshiyuki Tohno
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  3. Cho Azuma
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  4. Yumi Moriwake
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  5. Hiroyasu Satoh
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  6. Takeshi Minami
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  7. Pasuk Mahakkanukrauh
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  8. Takao Ohishi
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  9. Motoharu Hayashi
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Tohno, S., Tohno, Y., Azuma, C. et al. Decreases of calcium and phosphorus in monkey cardiac walls with development and aging. Biol Trace Elem Res 110, 233–249 (2006). https://doi.org/10.1385/BTER:110:3:233

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  • DOI: https://doi.org/10.1385/BTER:110:3:233

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