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Smoking does not influence cadmium concentrations in blood and urine in relatively high levels of environmental cadmium areas in Japan

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Abstract

We examined how the influence of smoking on blood and urinary cadmium (Cd) concentrations was modified by the level of environmental Cd. We measured blood and urinary Cd concentrations of 1134 men over 50 yr of age in three areas in Japan that were exposed to different levels of environmental Cd. Analysis of variance was used to compare Cd concentrations in blood and urine of smokers with those of nonsmokers living in the three areas. Correlation coefficients between the number of cigarets smoked per day or smoking indices (the number of cigarets smoked per day multiplied by the number of years smoked) and blood and urinary Cd concentrations were calculated. No significant difference in Cd concentrations between smokers and nonsmokers was observed in areas where the average Cd concentration in blood was over approx 2.4 ng/g, 2.0 μg/L in urine, and 2.3 μg/g creatinine in urine, respectively. Therefore, it was suggested that an influence of smoking on blood and urinary Cd concentrations was not observed in areas exposed to relatively high levels of environmental Cd.

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Authors and Affiliations

  1. Department of Occupational and Environmental Medicine, Graduate School of Medicine, Chiba University, Chuohku, Chiba, Japan

    Mirei Uetani, Etsuko Kobayashi, Yasushi Suwazono & Koji Nogawa

  2. Department of Public Health, Kanazawa Medical University, Japan

    Muneko Nishijo & Hideaki Nakagawa

  3. Department of Community Health Nursing, Kanazawa University School of Health Sciences, Japan

    Teruhiko Kido

Authors
  1. Mirei Uetani
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  2. Etsuko Kobayashi
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  3. Yasushi Suwazono
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  4. Muneko Nishijo
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  5. Hideaki Nakagawa
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  6. Teruhiko Kido
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  7. Koji Nogawa
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Uetani, M., Kobayashi, E., Suwazono, Y. et al. Smoking does not influence cadmium concentrations in blood and urine in relatively high levels of environmental cadmium areas in Japan. Biol Trace Elem Res 110, 107–117 (2006). https://doi.org/10.1385/BTER:110:2:107

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  • DOI: https://doi.org/10.1385/BTER:110:2:107

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