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Effect of zinc supplementation on hematological parameters in athletes

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Abstract

The hematological effects of oral supplementation of zinc to training athletes are reported in the present study. A total of 30 subjects between 16 and 22 yr of age volunteered to participate in a 4-wk study. They were equally divided into three groups. Group 1 acted as resting controls receiving daily doses of 3 mg Zn/kg body wt. Group 2 was actively engaged in wrestling and exercised for 90–120 min, 5 d a week. Group 3 was also actively engaged in wrestling and exercised for 90–120 min, 5 d a week, but they were supplemented with 3 mg Zn/kg body wt per day. The erythrocyte, leukocyte, and thrombocyte counts and the hemoglobin values of all subjects participating in the study were measured before and after exercise at the beginning and at the end of the 4-wk study period.

In all groups, there were no significant differences in the measured parameters before and after exercise. At the end of the supplementation period, the parameters of the subjects in groups 1 and 3 were significantly higher than those of group 2, both before (p<0.005) and after (p<0.05) exercise. These results suggest that zinc supplementation has a positive effect on hematological parameters in athletes.

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References

  1. A. K. Baltaci, Zinc and exercise, J. Gene. Med. 11, 129–133 (2001).

    Google Scholar 

  2. B. L. Vallee and K. H. Falchuk, The biochemical basis of zinc physiology, Physiol. Rev. 73, 79–127 (1993).

    PubMed  CAS  Google Scholar 

  3. A. S. Prasad, Clinical manifestations of zinc deficiency, Annu. Rev. Nutr. 5, 341–363 (1985).

    Article  PubMed  CAS  Google Scholar 

  4. S. Joatar, W. Chaisiripoomkere, O. Thaikla, et al., Effect of running exercise on hematological changes hematopoietic progenitor cells (CFU-GM) and fibrinolytic system in humans, J. Med. Assoc. Thai. 75, 94–98 (1992).

    Google Scholar 

  5. A. K. Baltaci, R. Mogulkoc, B. Ustundag, et al., A study on some hematological parameters and the levels of plasma proteins and serum zinc, calcium and phosphorus in young female athletes. J. Phys. Educ. Sports Sci. 3, 21–30 (1998).

    Google Scholar 

  6. Z. Szygula, Erythrocytic system under the influence of physical exercise and tarining, Sprots Med. 10, 181–197 (1990).

    CAS  Google Scholar 

  7. P. Vogelaere, M. Brasseur, R. Leclercq, et al., Hematological variations with submaximal long-term physical exercise, Can. J. Sports Sci. 13, 43–49 (1988).

    CAS  Google Scholar 

  8. K. E. Fallon, and G. Bishop, Changes in erythropoiesis assessed by reticulocyte parameters during ultralong distance running, Clin. J. Sports Med. 12, 172–178 (2002).

    Article  Google Scholar 

  9. N. Dönmez, H. H. Donmez, E. Keskin, et al., Effects of zinc supplementation to ration on some hematological parameters in broiler chicks, Biol. Trace Element Res. 87, 125–131 (2002).

    Article  Google Scholar 

  10. H. A. El Hendy, M. I. Yousef, and N. I. Abo El-Naga, Effect of dietary zinc deficiency on hematological parameters and concentration of zinc, copper, and iron in growing rats, Toxicology 167, 163–170 (2001).

    Article  PubMed  Google Scholar 

  11. S. Khaled, J. F. Brun, G. Cassanas, et al., Effects of zinc supplementation on blood rheology during exercise, Clin. Hemorheol. Microcirc. 20, 1–10 (1999).

    PubMed  CAS  Google Scholar 

  12. A. K. Baltaci, K. Ozyurek, R. Mogulkoc, et al., Effects of zinc deficiency and supplementation on some hematologic parameters of rats performing acute swimming exercise, Acta Physiol. Hung. 90, 125–132 (2003).

    Article  PubMed  CAS  Google Scholar 

  13. R. N. Podel, Zinc supplementation evidence of growth stimulation in sickle cell disease, Postgraduate Med. 76, 249–251 (1984).

    Google Scholar 

  14. A. Ece, B. S. Uyanik, A. Iscan, et al., Increased serum copper and decreased serum zinc levels in children with iron deficiency anaemia, Biol. Trace Element Res. 59, 31–39 (1997).

    CAS  Google Scholar 

  15. J. F. Brun, Exercise hemorheology as a three acts play with metabolic actors: is it of clinical relevance?, Clin. Hemorheol. Microcirc. 26, 155–174 (2002).

    PubMed  CAS  Google Scholar 

  16. A. Cordova, F. J. Navas, and J. F. Escanero, The effect of exercise ans zinc supplement on the hematological parameters in rats, Biol. Trace Element Res. 39, 13–20 (1993).

    CAS  Google Scholar 

  17. A. S. Prasad, Zinc and immunity, Mol. Cell. Biochem. 188, 63–69 (1998).

    Article  PubMed  CAS  Google Scholar 

  18. C. J. McClain, E. J. Kasarskis, and J. J. Allen, Functional consequenses of zinc deficiency, Prog. Nutr. Sci. 9, 195–226 (1985).

    Google Scholar 

  19. A. H. Shankar, and A. S. Prasad, Zinc and immune function: the biological basis of altered resistance to infections, Am. J. Clin. Nutr. 68, 447–463 (1998).

    Google Scholar 

  20. D. Konig, C. Weinstock, J. Keul, et al., Zinc, iron and magnesium status in athletes—influence on the regulation of exercise-induced stres and immune function, Exerc. Immunol. Rev. 4, 2–21 (1998).

    PubMed  CAS  Google Scholar 

  21. A. Ozturk, A. K. Baltaci, R. Mogulkoc, et al., Effects of zinc deficiency and supplementation on malondialdehyde and glutathione levels in blood and tissue of rats performing swimming exercise, Biol. Trace. Element Res. 94, 157–166 (2003).

    Article  CAS  Google Scholar 

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Kilic, M., Baltaci, A.K. & Gunay, M. Effect of zinc supplementation on hematological parameters in athletes. Biol Trace Elem Res 100, 31–38 (2004). https://doi.org/10.1385/BTER:100:1:031

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  • DOI: https://doi.org/10.1385/BTER:100:1:031

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