Abstract
Animal models of fibrodysplasia ossificans progressiva (FOP) are important for understanding the pathophysiology of FOP and for testing possible therapies. Laboratory-generated genetic animal models, each with features of FOP, provide the opportunity to better understand the biology of FOP, and to study the effectiveness and safety of currently available and emerging therapies.
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Kaplan, F.S., Shore, E.M., Pignolo, R.J. et al. Animal models of fibrodysplasia ossificans progressiva. Clinic Rev Bone Miner Metab 3, 229–234 (2005). https://doi.org/10.1385/BMM:3:3-4:229
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DOI: https://doi.org/10.1385/BMM:3:3-4:229