Abstract
This study assessed changes in corneal and conjunctional cytology in 25 soft contact lens (CL) wearers and compared them with matched controls. We found 80% of grade IV keratinization in CL users for more than 7 years. Keratinization was directly proportional to duration of CL use. Conjunctival cytological changes worsened with decreasing pH, whereas corneal keratinization showed no significant correlation.
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DiFiore's Atlas of Histology with Functional Correlations. 8th Ed. Eroschenko, VP, ed. Philadelphia: Williams and Wilkins, 1996.
Thoft RA, Friend J. Biochemical aspect of contact lens wear. Am J Ophthalmol 1975;80:139–145.
Lowther GE, Hill RM. Corneal epithelium recovery from anoxia. Arch Ophthalmol 1974;92:231–234.
Polse KA, Decker M. Oxygen tension under a contact lens. Invest Ophthalmol Vis Sci 1979;18:188–193.
Hassell JR, Newsome DA, DeLuca L. Increased biosynthesis of specific glyconjugates in rate corneal epithelium following treatment with vitamin A. Invest Ophthalmol Vis Sci 1980:19:642–647.
Kinoshita S, Friend J, Kiorpes TC, Thoft RA. Keratin like protein in corneal and conjunctival protein epithelium are different. Invest Ophthalmol Vis Sci 1983;24:577–581.
Coles WH, Jaros PA. Dynamic ocular surface pH. Br J Ophthalmol 1984;68:549–552.
Dahl H, Dahl C. Hydrogen in concentration of tear fluid in newborn infants. Acta Ophthalmol (Copenh) 1985;63:692–694.
Holden BA, Ross R, Jenkins J. Hydrogel contact lenses impede carbon dioxide efflux from the human cornea. Curr Eye Res 1987;6:1283–1290.
Milder B. The lacrimal apparatus. In: Moses RA, ed. Alder's Physiology of the Eye: Clinical Applications. St. Louis, MO: CV Mosby, 1975.
Nom MS. Tear fluid pH in normal, contact lens wearers and pathological cases. Arch Ophthalmol (Copenhag). 1988;66:485–489.
Carney LG, Hill RM: Human Tear pH: diurnal variations. Arch Ophthalmol. 1976;94:821–824.
Vinding T, Ericksen JS, Nielsen NV. The concentration of lysozyme and secretory 19A in tears from healthy persons with and without contact lens use. Acta Ophthalmol (Copenh) 1987;65:23–26.
Singh RK. Thesis submitted for M.S. (Ophthal). 1992; B.H.U., India.
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The authors have stated that they do not have a significant financial interest or other relationship with any product manufacturer or provider of services discussed in this article. The authors also do not discuss the use of off-label products, which includes unlabeled, unapproved, or investigative products or devices.
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Bhatia, R.P., Lipika, R., Garbyal, R.S. et al. Corneal and conjunctival impression cytology in soft contact lens wearers. Ann Ophthalmol 38, 117–120 (2006). https://doi.org/10.1385/AO:38:2:117
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DOI: https://doi.org/10.1385/AO:38:2:117