Skip to main content
Log in

Risk factors for intraocular pressure elevations after pupillary dilation in patients with open angles

  • Original Article
  • Published:
Annals of Ophthalmology

Abstract

Purpose

To determine risk factors for postdilation pressure elevations in patients with open angles.

Methods

Patients included in the study had angles open to at least scleral spur before and after dilation with 0.8% tropicamide and 2.5% phenylephrine.

Results

Included were 411 eyes. Risk factors for postdilation pressure elevations of 6 mmHg or more included miotic use and glaucoma (primary open angle, normal tension, and pseudoexfoliation).

Conclusions

Patients at risk should be closely monitored.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Harris LS. Cycloplegic-induced intraocular pressure elevations. A study of normal and open angle glaucomatous eyes. Arch Ophthalmol. 1968;79:242–246.

    PubMed  CAS  Google Scholar 

  2. Portney GL, Purcell TW. The influence of tropicamide on intraocular pressure. Ann Ophthalmol. 1975;7:31–34.

    PubMed  CAS  Google Scholar 

  3. Harris LS, Galin MA. Cycloplegic provocative testing. Effect of miotic therapy. Arch Ophthalmol. 1969;81:544–547.

    PubMed  CAS  Google Scholar 

  4. Shaw BR, Lewis RA. Intraocular pressure elevation after pupillary dilation in open angle glaucoma. Arch Ophthalmol. 1986;104: 1185–1188.

    PubMed  CAS  Google Scholar 

  5. Hill RA, Minckler DS, Lee M, Heuer DK, Baerveldt G, Martone JF. Apraclonidine prophylaxis for postcycloplegic intraocular pressure spikes. Ophthalmology. 1991;98:1083–1086.

    PubMed  CAS  Google Scholar 

  6. Musch DC, Lichter PR, Guire KE, Standardi CL. The collaborative initial glaucoma treatment study: study design, methods, and base-line characteristics of enrolled patients. Ophthalmology. 1999; 106:653–662.

    Article  PubMed  CAS  Google Scholar 

  7. Collaborative Normal Tension Glaucoma Study Group. Natural history of normal tension glaucoma. Ophthalmology. 2001;108: 247–253.

    Article  Google Scholar 

  8. Kass MA, Heuer DK, Higginbotham EJ, et al. The ocular hypertension treatment study. Arch Ophthalmol. 2002;120:701–713.

    PubMed  Google Scholar 

  9. Kristensen P. Mydriasis-induced pigment liberation in the anterior chamber associated with acute rise in intraocular pressure in open angle glaucoma. Acta Ophthalmol. 1965;43:714–724.

    Article  CAS  Google Scholar 

  10. Aggarwal JL, Beveridge B. Liberation of iris pigment in the anterior chamber. Br J Ophthalmol. 1971;55:544–549.

    PubMed  CAS  Google Scholar 

  11. Valle O. Effect of cyclopentolate on the aqueous dynamics in incipient or suspected open angle glaucoma. Acta Ophthalmol. 1973; 123:52–60.

    Google Scholar 

  12. Harris LS, Galin MA. Cycloplegic provocative testing. Arch Ophthalmol. 1969;81:356–358.

    PubMed  CAS  Google Scholar 

  13. Schimek RA, Lieberman WJ. The influence of Cyclogyl and Neo-Synephrine on tonographic studies of miotic control in open angle glaucoma. Am J Ophthalmol. 1961;51:781–784.

    PubMed  CAS  Google Scholar 

  14. Lee DA, Brubaker RF. Effect of phenylephrine on aqueous humor flow. Curr Eye Res. 1983;2:89–92.

    CAS  Google Scholar 

  15. Araie M. Acute effects of topical phenylephrine on aqueous humor dynamics and corneal endothelial permeability in man. Jpn J Ophthalmol. 1983;27:340–345.

    PubMed  CAS  Google Scholar 

  16. Becker B, Gage T, Kolker AE, Gay AJ. The effect of phenylephrine hydrochloride on the miotic-treated eye. Am J Ophthalmol. 1959;48: 313–321.

    PubMed  CAS  Google Scholar 

  17. Lee PF. The influence of epinephrine and phenylephrine on intraocular pressure. AMA Arch Ophthalmol. 1958;60:863–867.

    PubMed  CAS  Google Scholar 

  18. Jacobi PC, Dietlein TS, Luke C, Engles B, Krieglstein GK. Primary phacoemulsification and intraocular lens implantation for acute angle-closure glaucoma. Ophthalmology. 2002;109:1597–1603.

    Article  PubMed  Google Scholar 

  19. Yang CH, Hung PT. Intraocular lens position and anterior chamber angle changes after cataract extraction in eyes with primary angle-closure glaucoma. J Cataract Refract Surg. 1997;23:1109–1113.

    PubMed  CAS  Google Scholar 

  20. Hayashi K, Hayashi H, Nakao F, Hayashi F. Changes in anterior chamber angle width and depth after intraocular lens implantation in eyes with glaucoma. Ophthalmology. 2000;107:698–703.

    Article  PubMed  CAS  Google Scholar 

  21. Steuhl KP, Marahrens P, Frohn C, Frohn A. Intraocular pressure and anterior chamber depth before and after extracapsular cataract extraction with posterior chamber lens implantation. Ophthalmic Surg. 1992;23:233–237.

    PubMed  CAS  Google Scholar 

  22. Kurimoto Y, Park M, Sakaue H, Kondo T. Changes in the anterior chamber configuration after small-incision cataract surgery with posterior chamber intraocular lens implantation. Am J Ophthalmol. 1997;124:775–780.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Teresa C. Chen MD.

Additional information

This author has stated that she does not have a significant financial interest or other relationship with any product manufacturer or provider of services discussed in this article. The author also does not discuss the use of off-label products, which include unlabeled, unapproved, or investigative products or devices.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chen, T.C. Risk factors for intraocular pressure elevations after pupillary dilation in patients with open angles. Ann Ophthalmol 37, 69–76 (2005). https://doi.org/10.1385/AO:37:2:069

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1385/AO:37:2:069

Keywords

Navigation