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Establishing mathematical and physical models for the adsorption of biomacromolecules

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Abstract

In this article, a series of mathematical and physical models for the adsorption of biomacromolecules are established. As shown, the adsorption of biomacromolecules is actually considerably complicated and often involves various interactions, such as electrostatic, hydrophobic and hydrogen-bonding, etc. Considering this, these models show that if these interactions are heavily involved in the process, the plot of in Q (or Q) vs In C* is normally expected to be a straight-line. Otherwise, if the linearity exists between C*/Q vs C*, the adsorption would be an ideal process without the intervention of them. Meanwhile, this article also presents corresponding relationships for the adsorption in multisited binding and multilayer forms. Other aspects including ion-exchange systems are also discussed (C*, the equilibrium concentration of biomacromolecules; Q, the adsorbance).

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References

  1. Butler, J. E. (2000), Methods 22(1), 4–23.

    Article  CAS  Google Scholar 

  2. Brahim, S., Narinesingh, D., and Guiseppi-Elie, A. (2002), J. Mol. Catal. B. 18(3), 69–80.

    Article  CAS  Google Scholar 

  3. Panphilov, A. S. and Bekish, O. J. L. (1997), Immunol. Lett. 56(2), 462.

    Google Scholar 

  4. Glen, S. K., You, H. B., Harry, C., Jan, F. J., and Sung, W. K. (1992), J. Contr. Release 22(2), 83–93.

    Article  Google Scholar 

  5. Norman, E., Williams, P., and Illum, L. (1993), Biomaterials 14(3), 193–202.

    Article  CAS  Google Scholar 

  6. Lu, H. B., Homola, J. I., Campbell, C. T., Nenninger, G. G., Yee, S. S., and Ratner, B. D. (2001), Sens, Actuator B. 74(3), 91–99.

    Article  Google Scholar 

  7. Gessner, A., Paulke, B., and Müller, R. H. (2000), Electrophoresis 21(12), 2438–2442.

    Article  CAS  Google Scholar 

  8. Haynes, C. A., Sliwinsky, E., and Norde, W. (1994), J. Colloid Interf. Sci. 164(2), 263–514.

    Article  Google Scholar 

  9. Chatterjee, A., Ebina, T., and Iwasaki, T. (2001), Phys. Chem. A. 105(47), 10,694–10,701.

    Article  CAS  Google Scholar 

  10. Pei, R., Cui, X., Yang, X., and Iwasaki, T. (2001), Biomacromolecules 2 (2), 463–468.

    Article  CAS  Google Scholar 

  11. Yang, C. H. (1998), J. Colloid Interf. Sci. 208(2), 379–387.

    Article  CAS  Google Scholar 

  12. Zhou, D., Liu, X, Kaczmarski, K., Felinger, A., and Guiochon, G. (2003), Biotechnol. Prog. 19(3), 945–954.

    Article  CAS  Google Scholar 

  13. Calonder, C. and Van Tassel, P. R. (2001), Langmuir 17(14), 4392–4395.

    Article  CAS  Google Scholar 

  14. Van Tassel, P. R. (2003), Materialwissenschaft und Werkstofftechnik 34(12), 1129–1132.

    Article  Google Scholar 

  15. Gettens, R. T. T., Bai, Z. J., and Gilbert, J. L. (2005), J. Biomed. Mater. Res. A 72 (3), 246–257.

    Google Scholar 

  16. Sharma, S. and Agarwal, G. P. (2002), Adsorption 8(3), 203–213.

    Article  CAS  Google Scholar 

  17. Li, Z. J. (1990), in Kinetic Basis For Heterogeneous Catalysis (Li, Z. J., ed.), Beijing Univ. Press, Beijing, China, pp. 39–42.

    Google Scholar 

  18. Jiling University (1980), in Basis of Catalysis Action (Jiling Univ., ed.), Chin. Sci. Press, Beijing, China, pp. 1–30.

    Google Scholar 

  19. Wassell, D. H. T., Hall, R. H., and Embery, G. (1995), Biomaterials 16(9), 697–702.

    Article  CAS  Google Scholar 

  20. Li, R. S., Zhen, K.J., and Wang, G. J (1990), in Basis of Catalysis Action (Li, R. S., Zhen, K. J., and Wang, G. J., eds.), Chin. Sci. Press, Beijing, China, pp. 20–49.

    Google Scholar 

  21. Fu, X. C., Shen, W. X., and Yao, T. Y. (1998), in Physicochemistry (Fu, X. C., Shen, W. X., and Yao, T. Y., eds.) Chin. Higher Edu. Press, Beijing, China, pp. 937–942.

    Google Scholar 

  22. Li, S. J., Hu, J., and Liu, B. L. (2004), Method Findings Exper. Clin. Pharmacol. 26 (7), 507–513.

    Article  Google Scholar 

  23. Li, S. J., Hu, J., Liu, B. L. (2005), J. Chem. Technol. Biotechnol. 80(5), 531–536.

    Article  CAS  Google Scholar 

  24. Ziegler, A., Li-Blatter, X., Seelig, A., and Seelig, J. (2003), Biochemistry 42(30), 9185–9194.

    Article  CAS  Google Scholar 

  25. Todd, R. J., Johnson, R. D., and Arnold, F. H. (1994), J. Chromatogr. A. 662(1), 13–26.

    Article  CAS  Google Scholar 

  26. Todd, R. J., Johnson, R. D., and Arnold, F. H. (1994), J. Chromatogr. A. 662(1), 13–26.

    Article  CAS  Google Scholar 

  27. Sedlacek, J. and Nondek, L. (1985), J. High Resol. Chromastogr. 8(7), 364–365.

    Article  CAS  Google Scholar 

  28. Sircar, S. (1995), AIChE J. 41(5), 1135–1145.

    Article  CAS  Google Scholar 

  29. Johnson, R. D. and Arnold, F. H. (1995), Biochimica et Biophys. Act. 1247(2), 293–297.

    Google Scholar 

  30. Renard, J., Vidal-Madjar, C., Sebille, B., and Lapresle, C. (1995), J. Mol. Recogn. 8(1), 85–89.

    Article  CAS  Google Scholar 

  31. Li, S. J. and Liu, B. L. (2005), J. Graduate School Chin. Acad. Sci. 22(2), 179–186.

    Google Scholar 

  32. Gritti, F. and Guiochon, G. (2003), J. Colloid Interface Sci. 264(1), 43–59.

    Article  CAS  Google Scholar 

  33. Gritti, F., Götmar, G., Stanley, B. J., and Guiochon, G. (2003), J. Chromatogr. A. 988(2), 185–203.

    Article  CAS  Google Scholar 

  34. Piatkowski, W., Antos, D., Gritti, F., and Guiochon, G. (2003), J. Chromatogr. A. 1003(1), 73–89

    Article  CAS  Google Scholar 

  35. Ladiwala, A., Rege, K., Breneman, C. M., and Cramer, S. M. (2005), PNAS 102 (33), 11,710–11,715.

    Article  CAS  Google Scholar 

  36. Zhang, S. P. and Sun, Y. (2003), Ind. Eng. Chem. Res. 42(10), 1235–1243.

    Article  CAS  Google Scholar 

  37. Gerstner, J. A., Bell, J. A., and Cramer, S. M. (1997), Biophys. Chem. 52(1), 97–106.38.

    Google Scholar 

  38. Li, Y. and Pinto, N. G. (1995), J. Chromatogr. A. 702(2), 113–123.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, 430079, Wuhan, P. R. China

    Songjun Li, Pingchu Chen, Wuke Li, Xiao Hao & Guangfu Yang

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  1. Songjun Li
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  2. Pingchu Chen
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  3. Wuke Li
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  4. Xiao Hao
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  5. Guangfu Yang
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Correspondence to Pingchu Chen.

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Li, S., Chen, P., Li, W. et al. Establishing mathematical and physical models for the adsorption of biomacromolecules. Appl Biochem Biotechnol 134, 165–178 (2006). https://doi.org/10.1385/ABAB:134:2:165

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  • DOI: https://doi.org/10.1385/ABAB:134:2:165

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