Neuroinformatics

, Volume 5, Issue 1, pp 59–77 | Cite as

Voronoi analysis uncovers relationship between mosaics of normally placed and displaced amacrine cells in the thraira retina

  • Luciano Da Fontoura Costa
  • Daniela Maria Oliveira Bonci
  • Cézar Akiyoshi Saito
  • Fernando Allan De Farias Rocha
  • Luiz Carlos De Lima Silveira
  • Dora Fix Ventura
Original Article

Abstract

Although neuronal dynamics is to a high extent a function of synapse strength, the spatial distribution of neurons is also known to play an important role, which is evidenced by the topographical organization of the main stations of the visual system: retina, lateral geniculate nucleus, and cortex. The coexisting systems of normally placed and displaced amacrine cells in the vertebrate retina provide interesting examples of retinotopic spatial organization. However, it is not clear whether these two systems are spatially interrelated or not. The current work applies two mathematical-computational methods-a new method involving Voronoi diagrams for local density quantification and a more traditional approach, the Ripley K function-in order to characterize the mosaics of normally placed and displaced amacrine cells in the retina of Hoplias malabaricus and search for possible spatial relationships between these two types of mosaics. The results obtained by the Voronoi local density analysis suggest that the two systems of amacrine cells are spatially interrelated through nearly constant local density ratios.

Index Entries

Amacrine cells distance-based methods mosaics spatial correlation spatial order retina 

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Copyright information

© Humana Press Inc 2007

Authors and Affiliations

  • Luciano Da Fontoura Costa
    • 1
  • Daniela Maria Oliveira Bonci
    • 2
    • 3
  • Cézar Akiyoshi Saito
    • 4
  • Fernando Allan De Farias Rocha
    • 2
    • 4
  • Luiz Carlos De Lima Silveira
    • 4
    • 5
  • Dora Fix Ventura
    • 2
    • 3
  1. 1.Instituto de Física de São CarlosUniversidade de São PauloSão CarlosBrazil
  2. 2.Instituto de PsicologiaUniversidade de São PauloSão PauloBrazil
  3. 3.Núcleo de Neurociências e ComportamentoUniversidade de São PauloSão PauloBrazil
  4. 4.Departamento de FisiologiaUniversidade Federal do ParáBelémBrazil
  5. 5.Núcleo de Medicina TropicalUniversidade Federal do ParáBelémBrazil

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