Neurocritical Care

, Volume 5, Issue 3, pp 243–249 | Cite as

Mechanisms in neurogenic stress cardiomyopathy after aneurysmal subarachnoid hemorrhage

  • Vivien H. Lee
  • Jae K. Oh
  • Sharon L. Mulvagh
  • Eelco F. M. WijdicksEmail author


Cardiac dysfunction after aneurysmal subarachnoid hemorrhage (SAH) is often referred to as “neurogenic stunned myocardium,” which does not accurately reflect the suspected pathophysiology. We propose an alternativeterminology,” neurogenic stress cardiomyopathy,” as a more appropriate label based on our review of the current literature. This article will review the distinctive characteristics of SAH-induced cardiac dysfunction, hypotheses to explain the pathophysiology, and the supporting clinical and animal studies. Recognition of the unique features associated with SAH-induced cardiac complications allows optimal management of patients with SAH. We will also discuss the clinical and theoretical overlap of SAH-induced cardiac dysfunction with a syndrome known as tako-tsubocardiomyopathy and explore therapeutic opportunities.

Key wors

Subarachnoid hemorrhage cardiac apical ballooning tako-tsubo cardiomyopathy neurogenic stunned myocardium 


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Copyright information

© Humana Press Inc. 2006

Authors and Affiliations

  • Vivien H. Lee
    • 2
  • Jae K. Oh
    • 1
  • Sharon L. Mulvagh
    • 1
  • Eelco F. M. Wijdicks
    • 2
    Email author
  1. 1.Division of Cardiovascular DiseasesMayo Clinic College of MedicineRochester
  2. 2.Department of Neurology Division of Critical Care of NeurologyMayo Clinic College of MedicineRochester

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