Medical Oncology

, Volume 18, Issue 4, pp 289–291 | Cite as

Elevated serum cancer antigen 125 levels in advanced abdominal tuberculosis

  • V. Thakur
  • U. Mukherjee
  • K. Kumar
Case Report


A 48-yr-old female presented with a 1-yr history of pain in the hypochondrium and epigastrium. All routine investigations and computed tomography (CT) of the abdomen were done. CT findings revealed a welldefined cystic mass in the right ovary, and ascitis with features suggestive of secondaries over the omentum and peritoneal surface. The serum CA125 was 1255 U/mL (normal range 0–35 U/mL), which was indicative of ovarian malignancy. An exploratory laparotomy was performed. Histopathological examination of organs revealed the presence of granuloma. The patient was advised to undergo antitubercular treatment (ATT) and follow-up every month. After 1 mo of ATT, the CA125 level came down to 42 U/mL, which was near normal. As tuberculosis requires only a conservative management, we suggest that in cases of abdominopelvic mass with or without ascitis, high serum CA125 should always raise a suspicion of tuberculosis and a laparoscopy combined with peritoneal biopsy should be performed to confirm the diagnosis. This will prevent unnecessary laparotomies. Moreover, serum CA125 can be used to monitor the response of disease to antitubercular treatment.


Endometriosis Serum CA125 Serum CA125 Level Medical Oncology Volume Human Ovarian Carcinoma Cell 
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Copyright information

© Humana Press Inc 2001

Authors and Affiliations

  1. 1.Biochemistry Division, Department of Laboratory MedicineBatra Hospital and Medical Research CentreNew DelhiIndia
  2. 2.Pathology Division, Department of Laboratory MedicineBatra Hospital and Medical Research CentreNew DelhiIndia
  3. 3.Department of Onco SurgeryBatra Hospital and Medical Research CentreNew DelhiIndia

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