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Endocrine

, Volume 30, Issue 1, pp 45–53 | Cite as

Insulin resistance, the metabolic syndrome, diabetes, and cardiovascular disease risk in women with PCOS

  • H. J. Teede
  • S. Hutchison
  • S. Zoungas
  • C. Meyer
Article

Abstract

Polycystic ovary syndrome is the most common endocrinopathy of reproductive aged women affecting 6–10% of the population. Traditionally considered a reproductive disorder manifesting as chronic anovulation, infertility, and hyperandrogenism, management has primarily focused on short-term reproductive outcomes. Recently, however, significant metabolic aspects in conjunction with longer-term health sequalae of PCOS have been recognized. The metabolic features are primarily related to underlying insulin resistance (IR), which is now understood to play an important role in both the pathogenesis and long-term sequelae of PCOS.

Key words

Polycystic ovary syndrome cardiovascular disease arterial stiffness insulin resistance 

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Copyright information

© Humana Press Inc 2006

Authors and Affiliations

  • H. J. Teede
    • 1
  • S. Hutchison
    • 1
  • S. Zoungas
    • 1
  • C. Meyer
    • 1
  1. 1.Jean Hailes Research GroupMonash University Institute of Health Services Research and Diabetes Unit Southern HealthMelbourneAustralia

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