Biological Trace Element Research

, Volume 93, Issue 1–3, pp 63–74 | Cite as

Calcium, Phosphorus, calcium-phosphorus ratio in rib bone of healthy humans

  • Margaret Tzaphlidou
  • Vladimir Zaichick


Calcium and phosphorus concentrations as well as the Ca/P ratio were estimated in intact rib bone samples from healthy humans, 37 women and 45 men, aged 15–55 yr. For Ca and P concentration measurements, instrumental neutron activation analysis was used. The mean values (mean±SD) for the investigated parameters were 19.3±4.5% of dry bone weight, 8.42±2.14% of dry bone weight, and a ratio of 2.33±0.34, respectively. Statistically significant differences for the above parameters were not observed to be related either to age or sex. The mean values for Ca, P, and the Ca/P ratio were within a very wide range of published data and close to their medians. The individual variation for the Ca/P ratio in rib bone from healthy humans was lower than those for Ca and P taken separately. An indication is that the specificity of the Ca/P ratio improves upon that for Ca and P concentrations and may be more reliable in the diagnosis of bone disorders.

Index Entries

Calcium phosphorus Ca/P ratio human rib bone neutron activation analysis 


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Copyright information

© Humana Press Inc. 2003

Authors and Affiliations

  • Margaret Tzaphlidou
    • 1
  • Vladimir Zaichick
    • 2
  1. 1.Laboratory of Medical Physics, Medical SchoolIoannina UniversityIoanninaGreece
  2. 2.Radiological Research CentreKaluga RegionRussia

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