Biological Trace Element Research

, Volume 88, Issue 1, pp 25–30 | Cite as

Concentration of selenium in the whole blood and the thyroid tissue of patients with various thyroid diseases

  • M. Kucharzewski
  • J. Braziewicz
  • U. Majewska
  • S. Góźdź


We investigated the possible differences between the concentrations of selenium in the whole blood and thyroid tissue of patients with thyroid disease. The study comprises 41 women with nodular goiter, 19 women and 2 men with thyroid cancer, 18 women with Graves’ disease, and 7 women with thyroiditis. The concentration of selenium was determined by the TRXRF method. The lowest mean selenium level was achieved in the whole blood of women with Graves’ disease and the highest in the whole blood of healthy people. In the thyroid cancer tissue, we found the lowest concentration of selenium and the highest in the thyroid gland of women with nodular goiter and Graves’ disease. The low selenium levles in the thyroid tissue may increase thyroid cancer risk.

Index Entries

Trace element selenium thyroid disease 


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Copyright information

© Humana Press Inc 2002

Authors and Affiliations

  • M. Kucharzewski
    • 1
  • J. Braziewicz
    • 2
    • 3
  • U. Majewska
    • 2
    • 3
  • S. Góźdź
    • 2
  1. 1.Department of General SurgerySilesian Medical AcademyBytomPoland
  2. 2.Holycross Cancer CenterKielcePoland
  3. 3.Institute of PhysicsŚwiętokrzyska Academy in KielceKielcePoland

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