Advertisement

Biological Trace Element Research

, Volume 77, Issue 2, pp 131–138 | Cite as

Age-dependent changes of elements in human trachea

  • Setsuko Tohno
  • Yasuo Takano
  • Yoshiyuki Tohno
  • Yumi Moriwake
  • Takeshi Minami
  • Masako Utsumi
  • Masa-oki Yamada
  • Kazunari Yuri
Article

Abstract

To elucidate compositional changes of human trachea by aging, element contents in tracheae were determined by inductively coupled plasma-atomic emission spectrometry. The subjects consisted of seven men and seven women, ranging in age from 61 to 97 yr. The sulfur content of the tracheae decreased gradually with aging. In regard to calcium and phosphorus, both the contents increased to about three-fold amounts in their seventies compared with those in their sixties, and decreased thereafter. The contents of calcium and phosphorus were the highest in their seventies. Therefore, it is likely that surplus calcium released from bones is deposited temporally in the trachea, and the deposits are released from the trachea at older age. Based on our results of human cartilages, there are two types in regard to calcium accumulation: The first type is that calcium accumulation occurs progressively with aging; the second one is that calcium accumulation becomes the highest in the seventies or eighties, and decreases there-after. Therefore, the trachea belongs to the second type. Furthermore, the magnesium content remained constant through the age range.

Index Entries

Trachea calcium phosphorus sulfur aging human 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Y. Tohno, S. Tohno, T. Minami, M. Ichii, Y. Okazaki, M. Utsumi, et al., Age-related changes of mineral contents in human thoracic aorta and in the cerebral artery, Biol. Trace Element Res. 54, 23–31 (1996).Google Scholar
  2. 2.
    T. Araki and Y. Tohno, Age dependency of nanosecond fluorescence characteristics in human artery, Front. Med. Biol. Eng. 7, 265–273 (1996).PubMedGoogle Scholar
  3. 3.
    S. Tohno and Y. Tohno, Age-related differences in calcium accumulation in human arteries, Cell. Mol. Biol. 44, 1253–1263 (1998).PubMedGoogle Scholar
  4. 4.
    S. Tohno, M. Masuda, Y. Tohno, Y. Moriwake, T. Minami, M. Utsumi, et al., High accumulation of calcium and phosphorus in human iliac arteries, Biol. Trace Element Res. 70, 41–49 (1999).Google Scholar
  5. 5.
    S. Tohno, Y. Tohno, T. Minami, Y. Okazaki, M. Utsumi, F. Nishiwaki, et al., A high accumulation of minerals in human internal jugular vein, Biol. Trace Element Res. 62, 17–23 (1998).Google Scholar
  6. 6.
    S. Tohno, Y. Moriwake, Y. Tohno, T. Minami, F. Nishiwaki, M. Utsumi, et al., Age-related changes of element contents in human mitral and tricuspid valves, Biol. Trace Element Res. 70, 137–147 (1999).Google Scholar
  7. 7.
    Y. Tohno, S. Tohno, M. Utsumi, T. Minami, M. Ichii, Y. Okazaki, et al., Age-independent constancy of mineral contents in human vertebrae and auditory ossicles, Biol. Trace Element Res. 59, 167–175 (1997).Google Scholar
  8. 8.
    Y. Tohno, M. Utsumi, S. Tohno, T. Minami, Y. Okazaki, Y. Moriwake, et al., Age-dependent changes of mineral contents in man’s and woman’s calcanei, Biol. Trace Element Res. 60, 81–90 (1997).Google Scholar
  9. 9.
    Y. Tohno, M. Utsumi, S. Tohno, T. Minami, Y. Okazaki, Y. Moriwake, et al., A constancy of mineral contents in human auditory ossicles, Acta Anat. Nippon. 72, 531–534 (1997).PubMedGoogle Scholar
  10. 10.
    M. Utsumi, S. Tohno, T. Minami, Y. Okazaki, Y. Moriwake, M.-o. Yamada, et al., Age-independent constancy of mineral contents in human ribs, Biol. Trace Element Res. 67, 165–171 (1999).Google Scholar
  11. 11.
    S. Tohno, Y. Tohno, T. Minami, M. Ichii, Y. Okazaki, M. Utsumi, et al., Difference of mineral contents in human intervertebral disks and its age-related change, Biol. Trace Element Res. 52, 117–124 (1996).Google Scholar
  12. 12.
    S. Tohno, Y. Tohno, T. Minami, Y. Okazaki, M. Utsumi, Y. Moriwake, et al., High accumulations of calcium and phosphorus in woman’s pubic symphysis, Biol. Trace Element Res. 59, 177–185 (1997).Google Scholar
  13. 13.
    Y. Moriwake, Y. Tohno, S. Tohno, T. Minami, M. Utsumi, F. Nishiwaki, et al., Age-related changes of elements contents in the human meniscus, Biol. Trace Element Res. 64, 229–235 (1998).Google Scholar
  14. 14.
    Y. Takano, Y. Moriwake, Y. Tohno, T. Minami, S. Tohno, M. Utsumi, et al., Age-related changes of elements in the human articular disk of temporomandibular joint, Biol. Trace Element Res. 67, 269–276 (1999).Google Scholar
  15. 15.
    Y. Tohno, Y. Moriwake, Y. Takano, T. Minami, S. Tohno, M. Utsumi, et al., Age-related changes of elements in human anterior cruciate ligaments and ligamenta capitum femorum, Biol. Trace Element Res. 68, 181–192 (1999).Google Scholar
  16. 16.
    Y. Tohno, Y. Takano, S. Tohno, Y. Moriwake, T. Minami, M.-o. Yamada, et al., Age-dependent decreases of phosphorus and magnesium in human Achilles tendons, Biol. Trace Element Res. 74, 1–9 (2000).CrossRefGoogle Scholar
  17. 17.
    E. Kaellis, Histochemical demonstration of calcium in rat tracheal cartilages, Proc. Soc. Exp. Biol. Med. 130, 1325–1326 (1969).PubMedGoogle Scholar
  18. 18.
    C. R. Roberts and P. D. Pare, Composition changes in human tracheal cartilages in growth and aging, including changes in proteoglycan structure, Am. J. Physiol. 261, L92-L101 (1991).PubMedGoogle Scholar
  19. 19.
    R. M. Mason, Protein-polysaccharide complexes from adult human tracheal cartilage, Biochem. J. 119, 599–601 (1970).PubMedGoogle Scholar
  20. 20.
    S. Inerot and D. Heinegard, Articular cartilage proteoglycans in aging and osteoarthritis, in Glycoconjugates, Vol. 4, M. Horowitz, ed., Academic, New York, pp. 335–355 (1982).Google Scholar
  21. 21.
    Y. Tohno, S. Tohno, T. Minami, Y. Moriwake, M. Utsumi, F. Nishiwaki, et al., A possible balance of calcium accumulations among bone, cartilage, artery, and vein in single human individuals, Biol. Trace Element Res. 63, 105–111 (1998).Google Scholar
  22. 22.
    Y. Tateyama, Y. Takano, Y. Tohno, Y. Moriwake, S. Tohno, and T. Araki, Correlations of calcium accumulations among arteries, veins, cartilages, ligaments, and bones in single humans, Biol. Trace Element Res. 74, 211–221 (2000).CrossRefGoogle Scholar
  23. 23.
    P. J. Roughley and R. J. White, Age-related changes in the structure of the proteoglycan subunits from human articular cartilage, J. Biol. Chem. 255, 217–224 (1980).PubMedGoogle Scholar

Copyright information

© Humana Press Inc. 2000

Authors and Affiliations

  • Setsuko Tohno
    • 1
  • Yasuo Takano
    • 2
  • Yoshiyuki Tohno
    • 1
  • Yumi Moriwake
    • 1
  • Takeshi Minami
    • 3
  • Masako Utsumi
    • 1
  • Masa-oki Yamada
    • 1
  • Kazunari Yuri
    • 2
  1. 1.Laboratory of Cell Biology, Department of AnatomyNara Medical UniversityNaraJapan
  2. 2.Department of AnatomyKochi Medical SchoolKochiJapan
  3. 3.Department of Living Science and Program ProcessingKinki University Toyo-oka Junior CollegeHyogoJapan

Personalised recommendations