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Biological Trace Element Research

, Volume 113, Issue 2, pp 155–164 | Cite as

Effects of dietary arsenic levels on serum parameters and trace mineral retentions in growing and finishing pigs

  • L. Wang
  • Z. R. Xu
  • X. Y. Jia
  • X. Y. Han
Article

Abstract

This experiment was conducted to investigate the effect of dietary arsenic (As) levels on growth performance, serum biochemistry, and the retention of iron, copper, and zinc in tissues of growing and finishing pigs. Ninety-six crossbred pigs were randomly allotted to four dietary treatments. The corn-soybean basal diets were supplemented with 0, 10, 20, and 30 mg As/kg. Arsenic trioxide was used as the arsenic source. The feeding experiment lasted for 78d. The results showed that the high arsenic diet decreased average daily gain (ADG) (p<0.05) and increased feed gain ratio (F/G) (p<0.05). Arsenic intake significantly increased (p<0.05) serum γ-gultamyltransferase (GGT), glutamic-pyruvic transaminase (GPT), and alkaline phosphatase (ALP) activities, and decreased (p<0.05) total protein, urea nitrogen, creatinine, and triglycerides. Glutamic-oxalacetic transaminase (GOT) activity, albumin, and cholesterol were not affected (p>0.05). Arsenic feeding elevated (p<0.05) liver and kidney copper concentration, but reduced (p<0.05) copper concentration in heat, bile, and lymphaden of intestine mesentery. There were increases in iron levels in liver, bile, spleen, thymus, and pancreas in pigs fed the high As diets (p<0.05), but iron contents in kidney, heart, and serum were decreased by the arsenic treatment (p<0.05). Zinc concentrations were increased (p<0.05) in liver, kidney, and thymus of pigs with arsenic treatment, but decreased (p<0.05) in bile and lymphaden of intestine mesentery. This study suggested that high dietary As levels could alter serum biochemical parameters and the retention of copper, iron, and zinc in the viscera of growing and finishing pigs.

Index Entries

Arsenic growing and finishing pigs serum parameters trace mineral retention 

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Copyright information

© Humana Press Inc 2006

Authors and Affiliations

  • L. Wang
    • 1
  • Z. R. Xu
    • 1
  • X. Y. Jia
    • 1
  • X. Y. Han
    • 1
  1. 1.Key Laboratory for Molecular Animal Nutrition of Ministry of Education, Feed Science InstituteZhejiang UniversityHangzhouP. R. China

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