Biological Trace Element Research

, Volume 109, Issue 2, pp 97–104 | Cite as

Magnesium profile in autism

  • Mirella StrambiEmail author
  • Mariangela Longini
  • Joseph Hayek
  • Silvia Berni
  • Francesca Macucci
  • Elisa Scalacci
  • Piero Vezzosi


The aim of the present study was to determine and compare plasma and erythrocyte concentrations of magnesium in 12 autistic children (10 boys, 2 girls), 17 children with other autistic spectrum disorders (14 boys, 3 girls), 5 girls with classic Rett syndrome, and 14 normal children (7 boys, 7 girls) of the same age. No differences in intracellular Mg were found between controls and pathological subjects; however, autistic children and children with other autistic spectrum disorders had significantly lower plasma concentrations of Mg than normal subjects (p=0.013 and p=0.02, respectively). Although our study population was small, we conclude that children with autistic spectrum disorders require special dietary management. If these cases are diagnosed at an early stage, they can be helped through diet.

Index Entries

Autistic spectrum disorders autism erythrocyte magnesium plasma Rett syndrome 


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Copyright information

© Humana Press Inc. 2006

Authors and Affiliations

  • Mirella Strambi
    • 1
    Email author
  • Mariangela Longini
    • 1
  • Joseph Hayek
    • 2
  • Silvia Berni
    • 1
  • Francesca Macucci
    • 1
  • Elisa Scalacci
    • 1
  • Piero Vezzosi
    • 1
  1. 1.Department of Paediatrics, Obstetrics and Reproductive Medicine, Section of Neonatology and Preventive PaediatricsAzienda Universitaria Ospedaliera Senese, Policlinico Le ScotteSienaItaly
  2. 2.Neuropsychiatry UnitAzienda Universitaria Ospedaliera Senese, Policlinico Le ScotteSienaItaly

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