Applied Biochemistry and Biotechnology

, Volume 98, Issue 1–9, pp 687–698 | Cite as

Production of 1,3-propanediol by Klebsiella pneumoniae



1,3-Propanediol (1,3-PD) has numerous applications from polymers to cosmetics, foods, lubricants, and medicines. Recently, there are strong industrial interests in a new kind of polyester, polytrimethylene terephthalate, with 1,3-PD as a monomer. This new polyester shows significant promise for use in carpeting and textiles. In this article we introduce a mild aerobic fermentation process using a strain screened from Klebsiella pneumoniae ATCC 25955, which is insensitive to oxygen, to produce 1,3-PD. We also describe a two-step fermentation process starting with glucose that was converted into glycerol with a glycerol-producing yeast, followed by K. pneumoniae that converts glycerol into 1,3-PD without intermediate isolation and purification of glycerol.

Index Entries

1,3-Propanediol glycerol Klebsiella pneumoniae yeast fermentation 


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Copyright information

© Humana Press Inc. 2002

Authors and Affiliations

  1. 1.School of Chemical Engineering and Laboratory of Renewable Resources EngineeringPurdue UniversityWest Lafayette

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