Obesity Surgery

, Volume 16, Issue 5, pp 607–611 | Cite as

Histological Findings in the Liver Before and After Gastric Bypass

  • Attila Csendes
  • Gladys Smok
  • Ana Maria Burgos
Article

Background: Bariatric surgery results in massive loss of excess weight, changes in co-morbidities and improvement in quality of life. In these patients, liver histology taken before or during surgery reveals several histological abnormalities. In a prospective study of patients previously submitted to gastric bypass, we determined the changes in liver histology late after the surgery. Methods: In 16 out of a total of 557 patients who were submitted to open gastric bypass, a second liver biopsy was taken during the repair of an incisional hernia, performed at a mean of 17 months after the gastric bypass. Results: All patients had lost weight, now having a mean BMI of 28.6 kg/m2 (which had been 44.3 kg/m2 before gastric bypass). One patient with normal pre-operative liver histology remained normal at the second study. 11 out of 15 who had had liver abnormalities returned to a normal condition or had only minimal change (73.3%). 2 patients (13.3%) showed improvement, while 1 patient presented a slight worsening of liver condition. One patient who had had liver cirrhosis showed no change. Conclusion: Gastric bypass for morbid obesity is followed by a dramatic improvement or normalization of liver histological abnormalities in the great majority of the patients. Liver cirrhosis in the one patient remained unchanged.

MORBID OBESITY GASTRIC BYPASS LIVER HISTOLOGY HEPATIC STEATOSIS 

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Copyright information

© Springer 2006

Authors and Affiliations

  • Attila Csendes
    • Gladys Smok
      • Ana Maria Burgos

        There are no affiliations available

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