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Determination of Metaldehyde in Water by SPE and UPLC–MS–MS

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Abstract

A simple, rapid, sensitive and reliable analytical method for the determination of metaldehyde in water by ultra performance liquid chromatography-electrospray tandem mass spectrometry (UPLC–ESI–MS–MS) was developed. Water samples were directly purified on C18 cartridge. Then metaldehyde was eluted using 2 mL of methanol/water (85:15 v/v) and directly analyzed by UPLC–MS–MS on an Acquity BHE C18 column with methanol/20 mM ammonium acetate solution (85:15 v/v) as mobile phase. The samples were quantified with the external standard calibration curve method. Good linearity was obtained for metaldehyde at a concentration of 0.05–5 ng mL−1 with a linear relative coefficient >0.999. Recoveries of 96.1–106.3% with CVs of 2.61–4.77% were obtained. Limit of detection was 0.003 ng mL−1. The method demonstrated to be suitable for the determination of metaldehyde in water samples.

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Authors and Affiliations

  1. College of Agriculture, Hebei University of Engineering, Handan, 056038, People’s Republic of China

    Cun Li

  2. Ningbo Agriculture Products Quality Detector Center, Ningbo, 315040, People’s Republic of China

    Yin-Liang Wu, Ting Yang & Yan Zhang

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  1. Cun Li
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  2. Yin-Liang Wu
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  3. Ting Yang
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  4. Yan Zhang
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Correspondence to Yin-Liang Wu.

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Li, C., Wu, YL., Yang, T. et al. Determination of Metaldehyde in Water by SPE and UPLC–MS–MS. Chroma 72, 987–991 (2010). https://doi.org/10.1365/s10337-010-1761-0

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  • DOI: https://doi.org/10.1365/s10337-010-1761-0

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