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LC–MS Analysis of the Essential Oils of Achillea millefolium and Achillea crithmifolia

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Abstract

The chemical composition of the hydro-distilled essential oils of Achillea millefolium and Achillea crithmifolia was analyzed by GC, GC–MS, 13C NMR and high resolution LC–MS. For the first time, the use of the combination of different chromatographic and spectral methods, primarily the advantage of LC-Orbitrap over standard methods, enabled the detection of azulenes and their progenitors, in minute quantities, in previously believed proazulene free Achillea taxon (A. crithmifolia). Furthermore, the LC-Orbitrap hyphenated method provided the means for detection of these and related non-volatile (GC-injector compared to water steam distillation) metabolites up to know unreported as essential oil constituents.

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References

  1. Magiatis P, Skaltsounis A-L, Chinou I, Haroutounian SA (2002) Z Naturforsch C 57:287–290

    CAS  Google Scholar 

  2. Benedek B, Rothwangl-Wiltschnigg K, Rozema E, Gjoncaj N, Reznicek G, Jurenitsch J, Kopp B, Glasl S (2008) Pharmazie 63:23–26. doi:10.1691/ph.2008.7646

    CAS  Google Scholar 

  3. Si X-T, Zhang M-L, Shi Q-W, Kiyota H (2006) Chem Biodivers 3:1163–1180. doi:10.1002/cbdv.200690119

    Article  CAS  Google Scholar 

  4. Nemeth E (2005) J Essent Oil Res 17:501–512

    CAS  Google Scholar 

  5. Radulovic N, Zlatkovic B, Palic R, Stojanovic G (2007) Nat Prod Commun 2:453–474

    CAS  Google Scholar 

  6. Adams RP (2007) Identification of essential oil components by gas chromatography/mass spectrometry, 4th edn. Allured Publ Corp, Carol Stream, Illinois, USA

    Google Scholar 

  7. Kubeczka K-H, Formacek V (2002) Essential oil analysis by capillary gas chromatography and carbon-13 NMR spectroscopy, 2nd edn. Wiley, Chichester

    Google Scholar 

  8. Ramadan M, Goeters S, Watzer B, Krause E, Lohmann K, Bauer R, Hempel B, Imming P (2006) J Nat Prod 69:1041–1045

    Article  CAS  Google Scholar 

  9. Glasl S, Mucaji P, Werner I, Jurenitsch J (2003) Pharmazie 58:487–490

    CAS  Google Scholar 

Download references

Acknowledgments

The financial support of this work by the Ministry of Science and Technological Development of Serbia is gratefully acknowledged (142054B).

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Author notes

  1. Andrija Smelcerovic

    Present address: Department of Pharmacy, Faculty of Medicine, University of Nis, Bulevar Dr Zorana Djindjica 81, 18000, Nis, Serbia

Authors and Affiliations

  1. Institute of Environmental Research, Technical University of Dortmund, Otto-Hahn-Str. 6, 44221, Dortmund, Germany

    Andrija Smelcerovic & Marc Lamshoeft

  2. Department of Chemistry, Faculty of Science and Mathematics, University of Nis, Visegradska 33, 18000, Nis, Serbia

    Niko Radulovic, Danijela Ilic & Radosav Palic

Authors
  1. Andrija Smelcerovic
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  2. Marc Lamshoeft
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  3. Niko Radulovic
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  4. Danijela Ilic
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  5. Radosav Palic
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Corresponding author

Correspondence to Andrija Smelcerovic.

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Smelcerovic, A., Lamshoeft, M., Radulovic, N. et al. LC–MS Analysis of the Essential Oils of Achillea millefolium and Achillea crithmifolia . Chroma 71, 113–116 (2010). https://doi.org/10.1365/s10337-009-1393-4

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  • DOI: https://doi.org/10.1365/s10337-009-1393-4

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